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Nature Microbiology

Structural views of a C. diff toxin

Jan. 10, 2020—D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.

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Seeing the unseen: Vanderbilt science hub helps set a standard for innovative microbiome research, education

Dec. 19, 2019—The Vanderbilt Microbiome Initiative is receiving attention for its role as a standard bearer for other microbiome programs, thanks to a new article on the importance and emergence of microbiome centers – academic hubs of microbiome-related research.

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New target to stop Ebola

May. 21, 2018—A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members.

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Team isolates new antibodies that may aid RSV vaccine design

Feb. 9, 2017—Researchers at Vanderbilt University Medical Center (VUMC) have taken another step toward developing a vaccine against respiratory syncytial virus (RSV), the major cause of life-threatening pneumonia in infants worldwide.

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Research team takes aim at Ebola virus ‘decoy protein’

Aug. 11, 2016—Using an antibody generated at Vanderbilt University Medical Center that neutralizes the Ebola virus, researchers at the Scripps Research Institute in La Jolla, California, have determined the structure of a “decoy” protein that may enable the virus to evade detection by the immune system.

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Crystal structure reveals secrets of virulent bacterium

Jan. 14, 2016—Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States.

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