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myocardial infarction

Less inflammation = better healing

Oct. 17, 2019—Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes.

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Antibody “road block” enables fine-tuning for cardiac recovery, decreases risk of heart failure

Sep. 19, 2019—A new study published by Vanderbilt mechanobiology researchers details a possible solution for fine-tuning inflammation and cellular activity in cardiac recovery – thanks to an antibody initially developed for rheumatoid arthritis. 

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Going after the ‘heart attack gremlin’

Sep. 8, 2016—A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target.

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Delivering cells for heart repair

Jul. 10, 2015—A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.

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Reducing fatal rhythms after heart attack

Jul. 26, 2013—Reducing heart muscle response to calcium could decrease the risk of fatal arrhythmias after heart attacks.

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Fishing for heart attack repair tools

Jan. 5, 2012—Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool: zebrafish. The researchers visually screened...

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Heart attack repair kit

Aug. 16, 2011—A certain signaling pathway could be key to improving cardiac repair after a heart attack.

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