Monoclonal Antibodies
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Alphavirus “Achilles heel”
Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read MoreMay 17, 2018
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Study seeking to isolate antibodies against rabies virus
Few people die from rabid animal bites in the United States thanks to the near-universal availability of human rabies immune globulin and rabies vaccine, which are given as separate shots as soon as possible after exposure to the rabies virus. Read MoreApr 26, 2018
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Hope for an RSV vaccine
Newly discovered features in an RSV protein may be useful for rational structure-based vaccine design. Read MoreFeb 23, 2018
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Researchers find novel mechanism of resistance to anti-cancer drugs
Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance. Read MoreOct 17, 2017
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Researcher targets peanut allergies with Cohen Fund support
Scott Smith, M.D., Ph.D., assistant professor of Medicine, has received a 2017 research award from the Stanley Cohen Innovation Fund to test a new therapeutic strategy for peanut allergies. Smith's research could fundamentally change allergy treatment. Read MoreOct 12, 2017
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Team isolates new antibodies that may aid RSV vaccine design
Researchers at Vanderbilt University Medical Center (VUMC) have taken another step toward developing a vaccine against respiratory syncytial virus (RSV), the major cause of life-threatening pneumonia in infants worldwide. Read MoreFeb 9, 2017
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Preparing for a return of pox
To prepare for the potential of a smallpox return, Vanderbilt researchers are isolating and studying naturally occurring antibodies from the blood of previously infected or immunized people. Read MoreOct 20, 2016
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Research sheds light on how RSV wards off potential vaccines
Respiratory syncytial virus (RSV) is the major cause of life-threatening viral pneumonia in infants worldwide, yet despite repeated efforts, scientists have been unable to develop an effective vaccine against it. Read MoreOct 20, 2016
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Vanderbilt researchers identify potential antibody treatment for H7 avian flu
Researchers at Vanderbilt University Medical Center have isolated human antibodies against a type of bird flu that has killed more than 200 people in China since 2012 and which may pose a worldwide pandemic threat. Read MoreMar 7, 2016