Molecular Physiology And Biophysics
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Research Snapshot: Protons can tune synaptic signaling by changing the shape of a protein receptor
Research from Teru Nakagawa, professor of molecular physiology and biophysics, describes intricacies of normal brain function with implications for our understanding of brain injury and recovery: A decrease in pH can modify a neurotransmitter receptor’s structure, thereby modulating its location and kinetics. Read MoreAug 14, 2024
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David H. Wasserman, esteemed scientist and professor of molecular physiology and biophysics, has died
A fellow of the American Association for the Advancement of Science, David Wasserman led groundbreaking research studies on the role of physical exercise, insulin-stimulation and diet in metabolism Read MoreJun 25, 2024
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Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research
A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection, Read MoreOct 24, 2023
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A $3M NSF grant to advance biomanufacturing could help establish an innovative method to deliver medicines to cells
Trans-institutional project connects Vanderbilt experts in drug delivery, stem cell engineering, biomanufacturing and cell biology to advance biomanufacturing of nanoparticles that can deliver precisely targeted drugs to the site of a disease. Read MoreSep 28, 2023
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Study reveals genomic code for sepsis in the lungs and kidneys
Researchers at Vanderbilt University Medical Center and the Nashville Veterans Affairs Medical Center have “cracked” the genomic code for sepsis in the lungs and kidneys. Read MoreAug 21, 2023
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Two Vanderbilt School of Medicine Ph.D. students, their faculty advisers selected for HHMI Gilliam Fellows Program
Four Vanderbilt graduate students, faculty advisers named to Howard Hughes Medical Institute Gilliam Fellows Program for their leadership in science and commitment to advancing equity and inclusion in science. Read MoreAug 4, 2023
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Vanderbilt launches Center for Applied Artificial Intelligence in Protein Dynamics
Led by Vanderbilt University School of Medicine Basic Sciences professor Hassane Mchaourab, the Center for Applied Artificial Intelligence in Protein Dynamics will focus on the application of machine learning techniques to understand how proteins work. Read MoreApr 12, 2023
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Study explores possible drug target for neurological problems
A team at Case Western Reserve University and Vanderbilt University Medical Center has determined with atomic-level precision how two established drugs bind to and alter the conformation of a cell membrane transporter protein called NKCC1, shutting down its activity. Read MoreNov 3, 2022
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Study sheds light on the development of inflammation, high blood pressure and resulting kidney damage.
Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the development of inflammation, high blood pressure and resulting kidney damage. Read MoreOct 20, 2022
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Watch: Lab-to-Table Conversation: ‘Biomedical Research Ethics and the Scientific Method’
Join Hassane Mchaourab, the Louise B. McGavock Professor and professor of molecular physiology and biophysics, as he explores biomedical ethics with leading experts in law, biomedical research and basic sciences on Thursday, Sept. 29, from 11 a.m. to noon. Read MoreSep 20, 2022
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Study explores how bacteria become drug resistant
Vanderbilt researchers have revealed more of the inner-workings of a two-stage “molecular motor” in the cell membrane that enables bacteria to become resistant to drugs. Read MoreJan 6, 2022
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Learn about the science of longevity with Vanderbilt experts in virtual event
The School of Medicine Basic Sciences’ monthly Lab-to-Table Conversation will bring together research experts on Tuesday, Nov. 30, for a virtual discussion about our current understanding of the biology of longevity. Read MoreNov 15, 2021
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Uncovering how injury to the pancreas impacts cancer formation
Research from scientists at the School of Medicine Basic Sciences and the Salk Institute for Biological Studies shows that cells in the pancreas form new cell types to mitigate injury but are then susceptible to cancerous mutations. Read MoreOct 29, 2021
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Cohen Innovation Fund Awards Announced Supporting Two High-Risk, High-Reward Projects
Houra Merrikh, professor of biochemistry, and Teru Nakagawa, associate professor of molecular physiology and biophysics, have both been selected to receive one-year research awards from the Stanley Cohen Innovation Fund. The awards will support groundbreaking and paradigm-shifting research. Read MoreSep 28, 2021
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VU graduate students highlight contributions of Black scientists as part of Juneteenth celebration
In honor of this year’s Juneteenth holiday, Vanderbilt University graduate students from the Department of Molecular Physiology and Biophysics created a poster charting key achievements from Black scientists stretching back to 1837. Read MoreJun 16, 2021
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Research Snapshot: Neuroimaging study discovers alterations in brain circuits that contribute to alcohol use disorder
Research Snapshot: Neuroimaging research is the first to show an area of the brain’s role in early abstinence from alcohol, revealing key sex differences. Est. reading time 2.5 mins. Read MoreMay 11, 2021
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Vanderbilt research: Better understanding of fundamental cell behavior can improve drug development
Gregor Neuert has discovered that cells respond differently to acute and gradual stress. This finding will transform how cell signaling is understood and inform the drug discovery processes. Read MoreApr 13, 2021
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Early research shows promise for therapeutics that delay Type 2 Diabetes
Discovering the mechanism behind cell behavior that is a hallmark of type 2 diabetes, Vanderbilt researchers move closer to treatments for the disease, which affects 34 million Americans. Read MoreJan 12, 2021
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Vanderbilt University anti-inflammatory therapy licensed to Amytrx is now in clinical trials for eczema treatment
Jacek Hawiger’s anti-inflammatory peptide therapy, licensed by Amytrx and now in clinical trials, has the potential to safely and effectively treat a multitude of inflammatory and metabolic diseases. Read MoreOct 27, 2020
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Vanderbilt researchers develop publicly available COVID-19 animal susceptibility prediction tool; suggests increased risk to horses
All-remote collaboration results in free animal susceptibility tool to help prioritize research and closer examination of at-risk species. Read MoreOct 6, 2020