Molecular Cell
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Researchers discover that protein switches functions to regulate DNA replication
Vanderbilt biochemists have discovered that the protein RADX has different biological effects at sites of DNA synthesis, depending on the cellular conditions — even though it works the same way in both stressed and unstressed cells. Read MoreJul 22, 2021
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Gene network for leukemia factor
A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment. Read MoreFeb 4, 2021
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New method captures early viral-host protein interactions
Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins. Read MoreMay 7, 2020
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New tool probes gene regulation
Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. Read MoreFeb 6, 2020
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Study identifies protein’s role in chemotherapy resistance
Researchers at Vanderbilt University Medical Center (VUMC) have discovered a protein that may lead to a new way to prevent resistance and improve outcomes for patients whose cancers have mutations in the tumor suppressor gene BRCA2. Read MoreJul 20, 2017
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Study helps clarify components of DNA ‘copy machine’
Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery. Read MoreNov 12, 2015
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Study reveals how protein helps cells tolerate DNA damage
Vanderbilt and Stanford investigators have discovered how a protein that's part of the DNA replication "machinery" helps cells tolerate DNA damage. Read MoreJul 16, 2015
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‘Docking stations’ on chromosomes new anti-cancer target
Vanderbilt University researchers have discovered a cleft in a chromosome-binding protein that may hold the key to stopping most cancers in their tracks. Read MoreMar 26, 2015