MicroRNA
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MicroRNAs in immune cells help protect against metabolic defects in obesity: study
Vanderbilt researchers have demonstrated that a cluster of microRNAs — small pieces of RNA that regulate gene expression — work in a type of immune cells called macrophages to help protect against metabolic defects in obesity. Read MoreSep 5, 2023
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Putting the brakes on sepsis
An enzyme called PTEN reduces inflammatory signaling and mortality in sepsis, suggesting it may be a good therapeutic target for this life-threatening complication of infection. Read MoreMay 9, 2018
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Aqueous humor, microRNAs and glaucoma
New findings highlight microRNAs — molecules that regulate gene expression — that are differentially expressed in glaucoma and could be candidate biomarkers or targets for therapy. Read MoreApr 10, 2018
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An Argonaute’s voyage to cancer
A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.” Read MoreApr 28, 2016
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Study identifies new culprit in lung cancer development
A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered. Read MoreJan 27, 2016
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Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
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Network approach yields glioblastoma clues
MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor. Read MoreAug 9, 2012