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metastasis

Cancer cells combine tools to increase invasiveness

Dec. 19, 2013—Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered.

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Polarity protein suppresses tumor growth, invasion

Nov. 29, 2012—The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model.

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Proteins help flip tumor’s invasive switch

Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

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On the hunt for bladder cancer factors

Jul. 26, 2012—A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.

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Proteins guard against cancer spread

Jul. 24, 2012—Targeting immune system proteins may keep prostate cancer from spreading to bone.

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VU study finds stress fuels breast cancer metastasis to bone

Jul. 18, 2012—Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.

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Cancer study seeks clues to halting metastasis’ march

Aug. 10, 2011—Vanderbilt researchers have identified small molecules that can restore normal protein expression in human colorectal carcinoma cells and prevent invasive cancer growth.

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Integrin curbs cancer’s spread

Feb. 16, 2011—Cell surface molecules called integrins have been found to play an important role when cancer metastasizes.

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