Medicine
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Targeting post-transplant diabetes
Targeting diabetes that develops after a stem cell transplant may help moderate graft-vs.-host disease, an adverse effect of the procedure, and improve outcomes. Read MoreApr 12, 2012
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New tool hooks heart failure drugs
A new screening tool – using glowing fish embryos – could identify therapeutics for myocardial hypertrophy and heart failure. Read MoreApr 6, 2012
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Plant compound quells inflammation
Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases. Read MoreApr 6, 2012
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Gut germs govern growth
Treating H. pylori infection in children may help their growth rebound, a recent study suggests. Read MoreApr 6, 2012
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Obesity turns “good” cholesterol bad
Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol. Read MoreMar 21, 2012
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Urine biomarker for colon cancer?
A molecule detectable in urine may be helpful in diagnosing colon cancer. Read MoreMar 10, 2012
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Combo combats dizziness
Some patients may need a combo of medications to combat a condition that causes dizziness. Read MoreMar 9, 2012
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‘Detangler’ binds, bends and cuts DNA
New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents. Read MoreMar 2, 2012
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Stem cells take heart
Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle. Read MoreFeb 20, 2012
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Digestive disease research bolstered by grant renewal
The Vanderbilt Digestive Disease Research Center celebrates its 10th anniversary this year with a second five-year renewal of its federal research grant. Read MoreJan 20, 2012
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Study applies random genotype sets to new disease
A new study in the American Journal of Human Genetics, led by Vanderbilt researchers Josh Denny, M.D., M.S., and Dana Crawford, Ph.D., takes random volumes of human genotypes and matches them with data siphoned from de-identified medical records and sheds new light on the genetic basis of the common… Read MoreJan 5, 2012
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Melatonin found to ease sleep woes in children with autism
Vanderbilt researchers are studying how the supplement melatonin can ease the sleep difficulties that often afflict children with autism spectrum disorders. (iStock) A new Vanderbilt study shows that the over-the-counter supplement melatonin is promising in helping children with autism spectrum disorders (ASD), and their families, sleep better. Read MoreJan 5, 2012
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Clues to skeletal form in ‘feelgood’ fish
Ela Knapik, associate professor of medicine, and colleagues are using zebrafish to explore the molecular and cellular mechanisms that cause birth defects of the face and skeleton. Read MoreDec 16, 2011
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New schizophrenia drug candidates entering prep for first-in-human testing
The progression of new drug candidates for schizophrenia with partner Janssen Pharmaceutica is the latest evidence that a new collaborative model for drug discovery pioneered at Vanderbilt may help identify and develop innovative candidate drugs for treatment of major brain disorders. Read MoreDec 15, 2011
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Offspring of childhood cancer survivors have no increased risk for birth defects
Children of childhood cancer survivors who were treated with radiation or some forms of do not have an increased risk for birth defects compared to children of cancer survivors who did not receive such treatments. Read MoreDec 15, 2011
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Jeffrey Sosman named to melanoma research ‘Dream Team’
Jeffrey Sosman (Vanderbilt) Jeffrey Sosman, professor of medicine at Vanderbilt-Ingram Cancer Center (VICC), has been named to a melanoma research Dream Team of cancer investigators supported by Stand Up To Cancer (SU2C) and the Melanoma Research Alliance. Sosman is among the Dream Team’s principal investigators who… Read MoreDec 15, 2011
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Study leads to simpler therapy for treating latent tuberculosis
Research led by Timothy Sterling, professor of medicine, has led to an important change in The Centers for Disease Control and Prevention's recommendations in the regimen for prevention of the centuries-old scourge, tuberculosis. Read MoreDec 9, 2011
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Exercise fights fatty liver
(iStock) Fatty liver, a reversible condition of fat accumulation in liver cells, can result from excessive alcohol consumption, obesity, type 2 diabetes, or metabolic disorders. Exercise can reverse this process, but the mechanisms underlying this effect are not clear. Because exercise is known to stimulate the action of glucagon (a… Read MoreNov 18, 2011
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Skeletal defects in genetic disorder
A new mouse model provides a tool for testing novel therapeutic approaches for neurofibromatosis. Read MoreNov 18, 2011
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VUCast: Vanderbilt Bookstore grand opening
This Week on VUCast, Vanderbilt’s weekly newscast highlighting research, experts, students, sports and everything Vanderbilt: experience the grand opening of the new Vanderbilt Bookstore the dangers and solutions for handling old medicine and Peabody through the centuries [vucastblurb]… Read MoreNov 14, 2011