Medicine
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Factor reduces virus-related asthma attacks
An immune system factor associated with severe asthma may actually reduce asthma attacks induced by viral infections. Read MoreApr 26, 2013
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‘Longevity’ gene aids kidney survival
A gene associated with cell survival and longevity may protect the kidney from acute injury. Read MoreApr 17, 2013
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Lung damage protector
Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue. Read MoreApr 12, 2013
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Leukemia culprit’s cellular actions
Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous. Read MoreApr 11, 2013
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“Silent” B cells trigger autoimmunity
Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes. Read MoreApr 3, 2013
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Acetaminophen: protective in sepsis?
In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen. Read MoreMar 28, 2013
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Bacterial resistance breaks bridges
Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs. Read MoreMar 14, 2013
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Tick-tock – predicting menopause
An ultrasound count of potentially egg-producing follicles could predict the timing of menopause. Read MoreMar 6, 2013
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Target for inflammatory bowel disease
The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments. Read MoreMar 1, 2013
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Factor CITED in pediatric liver cancer
Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer. Read MoreFeb 20, 2013
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Cell connections key in valve disease
A protein that connects cells together participates in the calcification that occurs in heart valve disease. Read MoreFeb 14, 2013
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Study tracks genes involved in heart rhythm disorders
A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm. Read MoreFeb 7, 2013
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Linking oxygen, iron and red blood cells
The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance. Read MoreFeb 6, 2013
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Do-it-yourself repair in the kidney
The kidney can mediate its own repair through proliferation of resident immune system cells. Read MoreJan 31, 2013
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HDL cholesterol impaired in kidney disease
HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read MoreJan 21, 2013
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Cancer markers from archived tissue
Archived tissue samples are yielding new disease biomarkers. Read MoreDec 20, 2012
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Genetic clues to lung scarring
A rare genetic syndrome provides new clues to lung scarring (pulmonary fibrosis), a potentially deadly consequence of many lung diseases. Read MoreDec 10, 2012
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‘Longevity’ gene has role in bone loss
A gene associated with long life participates in the normal regulation of bone remodeling and may have a role in bone loss associated with aging. Read MoreDec 6, 2012
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New faculty: John Graves plays role in shaping national health policy
John Graves was part of the team hired by the Obama administration to provide statistical and economic evidence that would inform the development of the Affordable Care Act. Read MoreNov 20, 2012
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Bird’s eye view of gut development
A new map of the developing gut of quail offers valuable tool for studying intestinal diseases. Read MoreNov 19, 2012