Leukemia

Vanderbilt researchers identified a critical role for IL-1beta signaling in leukemia cells with a certain mutation, suggesting this pathway may be a good target for novel treatments. Read More

Using primary cells from patients with chronic myelomonocytic leukemia, Vanderbilt researchers found synergistic inhibition of cell viability and proliferation, suggesting a new treatment strategy. Read More

A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment. Read More

A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found. Read More

A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients. Read More

Monroe Carell Jr. Children’s Hospital at Vanderbilt is part of a select group of health care institutions recently chosen to offer a new FDA-approved immunotherapy for a subset of pediatric acute lymphoblastic leukemia (ALL). Only 32 health care institutions in the United States will be certified to offer the therapy. Read More

Modulation of T cell metabolism thus may represent a new therapeutic avenue for leukemia patients. Read More

A Vanderbilt patient who has battled leukemia for nearly five years was granted a private screening of “Star Wars: The Force Awakens,” thanks to her medical providers and a local movie theater. Read More

It’s not unusual to see dogs in a hospital setting, but is there scientific evidence that man’s best friend help’s children? Vanderbilt researchers are working to find that answer as Barb Cramer reports.                  … Read More

A new mouse model reveals gene clusters important in a treatment-resistant form of leukemia. Read More

Emmanuel Volanakis, M.D., assistant professor of Pediatrics and Hematology/Oncology, was awarded a $250,000 Hyundai Hope On Wheels grant last week for his ongoing research into T-cell acute lymphoblastic leukemia (ALL), an aggressive blood cancer. Read More

Puck Ohi, Ph.D., assistant professor of Cell and Developmental Biology, has received the Leukemia & Lymphoma Society SCHOLAR award for his research on the role of enzymes that affect cell division, which has implications for treating cancer and blood disorders like leukemia and lymphoma. Read More

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous. Read More