Kleberg Foundation
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Gene network for leukemia factor
A new method speeds the analysis of factors that control gene expression from days to minutes, allowing researchers to uncover new targets for cancer treatment. Read MoreFeb 4, 2021
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WIN for blocking cancer growth
William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth. Read MoreJan 21, 2021
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Pancreatic cancer development
Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read MoreAug 31, 2017
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HDAC3 role in B-cell development
The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies. Read MoreAug 3, 2017
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PET imaging to predict tumor response
A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models. Read MoreJun 14, 2017
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New grants bolster Trauma program’s research initiatives
Vanderbilt University Medical Center’s Division of Trauma, Emergency General Surgery and Surgical Critical Care was recently awarded two new research grants. Read MoreFeb 9, 2017
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Kleberg Foundation grant bolsters cancer drug discovery efforts
The Robert J. Kleberg Jr. and Helen C. Kleberg Foundation has awarded a $3 million grant to Vanderbilt-Ingram Cancer Center (VICC) investigators in support of VICC’s drug discovery program. The gift awarded over the next three years from the private, San Antonio, Texas-based foundation will enable VICC researchers to pursue the development of new compounds to block the activity of cancer-causing genes and proteins that had previously been considered “undruggable.” Read MoreAug 3, 2016
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New lead for ovarian cancer treatment
Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer. Read MoreDec 10, 2015
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Growth factor blockade targets breast tumors
Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis. Read MoreAug 14, 2014
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PET probe detects dying tumor cells
A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine. Read MoreMay 8, 2014