Kidney Disease

  • Human kidney cross section on scientific background. 3d illustration

    Gene expression in diabetic nephropathy

    Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read More

    Aug. 5, 2021

  • Vanderbilt University

    Clue to diabetic kidney disease

    Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read More

    Oct. 5, 2020

  • Photo of rolled-up blueprints on drafting desk

    Study shines light on architecture of kidney disease

    A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues. Read More

    Sep. 25, 2019

  • cropped photo of older african american man holding his hands to his chest as if in pain

    Diabetes drug study explores cardiovascular risks for patients with kidney disease

    An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease. Read More

    Sep. 25, 2019

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    Sex differences in kidney injury

    Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor. Read More

    Jul. 25, 2019

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    Kidney disease imaging

    Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read More

    Mar. 22, 2018

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    Research explores barriers to kidney disease screening

    New research by Vanderbilt nephrologists highlights potential barriers that may prevent black Americans from being screened for kidney disease. Read More

    Mar. 15, 2018

  • VIGH receives federal grants to fight kidney disease

    VIGH receives federal grants to fight kidney disease

    Researchers in the Vanderbilt Institute for Global Health (VIGH) have received two new grants from the National Institutes of Health (NIH) aimed at reducing the risk of kidney disease in HIV-infected adults and improving the treatment of epilepsy in children in Nigeria. Read More

    Oct. 12, 2017

  • Major grant to enhance kidney disease research

    Major grant to enhance kidney disease research

    Vanderbilt’s Division of Nephrology and Hypertension has received a five-year, $5 million federal grant to provide core research services in the fight against kidney disease. Read More

    Sep. 28, 2017

  • Vanderbilt University

    End-stage kidney disease study seeks to delay dialysis

    Vanderbilt University Medical Center (VUMC) is studying the safety of a possible treatment for diabetic kidney disease that would delay or prevent the need for kidney replacement such as dialysis. Read More

    Aug. 31, 2017

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    How to build a basement

    Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer. Read More

    Sep. 9, 2015

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    Study: Why one kidney can work as well as two

    Vanderbilt University researchers have come closer to solving a mystery that has puzzled scientists for more than a century: after the loss of one kidney, what causes the growth of the remaining kidney to take up the slack? Read More

    Jun. 11, 2015

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    Kidney disease impacts HDL function

    Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month. Read More

    Feb. 11, 2015

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    NIH grant spurs diabetic nephropathy research

    Diabetic nephropathy, or kidney disease caused by diabetes, is a major source of morbidity and mortality. In the United States, more than 30 percent of patients receiving either dialytic therapy or renal transplantation have end stage renal disease as a result of diabetic nephropathy. Read More

    Oct. 30, 2014

  • Raymond Harris

    New Center Takes on Kidney Disease

    Kidney disease is the eighth most common cause of death in the United States and affects more than 20 million people, yet many people don’t know they have it because kidney disease often develops slowly with minimal symptoms. Read More

    Sep. 26, 2014

  • Vanderbilt University

    Molecular ‘chat’ holds kidney fibrosis clues

    A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process. Read More

    Jul. 10, 2014

  • Vanderbilt University

    New center dedicated to kidney disease

    Kidney disease is the eighth most common cause of death in the United States and affects more than 20 million people, yet many people don’t know they have kidney disease because it often develops very slowly and with minimal symptoms. For this reason, kidney disease is often referred to as a silent killer. Read More

    May. 29, 2014

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    Small molecule protects kidney filter

    A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier. Read More

    Mar. 19, 2014

  • Vanderbilt University

    Project seeks to create ‘bioartificial’ kidney

    Nephrologist William Fissell IV, M.D., associate professor of Medicine and Biomedical Engineering, is intent on creating and mass-producing an implantable bioartificial kidney that can transform quality of life and prospects for survival for people with chronic kidney disease who would otherwise be forced onto dialysis. Read More

    Jul. 11, 2013

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    HDL cholesterol impaired in kidney disease

    HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk. Read More

    Jan. 21, 2013