Kidney Disease

Clintoria Williams, associate professor in the Department of Neuroscience, Cell Biology and Physiology at Wright State University, has received the John F. Perkins, Jr. Research Career Enhancement Award from the American Physiological Society. This will enable her to join Vanderbilt as a visiting scholar in the Department of Molecular Physiology and Biophysics for four months to collaborate more closely with Antentor Hinton Jr., assistant professor in the department. Read More

Researchers at Vanderbilt University Medical Center have identified Rac1, a molecular switch that regulates the actin cytoskeleton of epithelial cells in the collecting ducts, as a driver of post-obstructive kidney repair. Read More

Vanderbilt computer scientist Yankai Huo is working with key clinical collaborators at Vanderbilt University Medical Center to develop a quantitative and reproducible 3D analytics tool for large-scale digital analysis of kidney tissues and biopsies. Read More

Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney. Read More

Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury. Read More

Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the development of inflammation, high blood pressure and resulting kidney damage. Read More

Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity. Read More

Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure. Read More

A new method developed by Vanderbilt researchers to generate kidney cells from stem cells offers a faster and less expensive way to make these valuable tools for studying kidney diseases. Read More

Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read More

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read More

A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues. Read More

An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease. Read More

Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor. Read More

Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read More

New research by Vanderbilt nephrologists highlights potential barriers that may prevent black Americans from being screened for kidney disease. Read More

Researchers in the Vanderbilt Institute for Global Health (VIGH) have received two new grants from the National Institutes of Health (NIH) aimed at reducing the risk of kidney disease in HIV-infected adults and improving the treatment of epilepsy in children in Nigeria. Read More

Vanderbilt’s Division of Nephrology and Hypertension has received a five-year, $5 million federal grant to provide core research services in the fight against kidney disease. Read More

Vanderbilt University Medical Center (VUMC) is studying the safety of a possible treatment for diabetic kidney disease that would delay or prevent the need for kidney replacement such as dialysis. Read More

Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer. Read More