Kidney
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VUMC researchers upend dogma about vasopressin production
Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney. Read MoreJan 5, 2023
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The role of integrins in kidney “integrity”
Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered. Read MoreJan 13, 2022
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New insights into kidney development
Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function. Read MoreApr 15, 2021
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Implant one day may replace dialysis
Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device. Read MoreMay 18, 2020
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Kidney disease imaging
Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury. Read MoreMar 22, 2018
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Cell skeleton and the brush border
Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines. Read MoreJan 31, 2018
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Motoring to the tips of the brush border
New findings implicate a motor protein in the assembly of the brush border in the intestines and kidneys – a specialized surface that is critical for healthy organ function. Read MoreOct 6, 2016
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Immune system a must for kidney repair
A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells. Read MoreNov 12, 2015
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VUMC receives NIH grant to develop artificial kidney
The National Institutes of Health has awarded a four-year, $6 million grant to investigators at Vanderbilt University Medical Center (VUMC) and the University of California at San Francisco (UCSF) to develop an implantable artificial kidney. Read MoreNov 3, 2015
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Surprising finding in the kidney
TGF-beta signaling in the kidney was thought to be a target for reducing renal fibrosis, but Vanderbilt researchers report that fibrosis still occurs in the absence of TGF-beta signaling. Read MoreApr 16, 2015
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VUCast: Ingenious Inventions
In the latest VUCast: Check out some creative inventions by Vanderbilt students; see how a "bionic man" has ties to Vanderbilt; and learn details about a new academic building under construction on campus. All this and more in the latest VUCast, Vanderbilt's online newscast. Watch now. Read MoreMay 21, 2014
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Small molecule protects kidney filter
A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier. Read MoreMar 19, 2014
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‘Longevity’ gene aids kidney survival
A gene associated with cell survival and longevity may protect the kidney from acute injury. Read MoreApr 17, 2013
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Woman gives ultimate Valentine’s gift to her husband
Kim Duncan donated a kidney to her husband, Thomas, on Valentine’s Day last week. (photo by Daniel Dubois) For the nearly 25 years Thomas Duncan has been married, he was crowned the king of Valentine’s Day gift giving. Not this year however, says his wife, Kim, who… Read MoreFeb 14, 2013
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Do-it-yourself repair in the kidney
The kidney can mediate its own repair through proliferation of resident immune system cells. Read MoreJan 31, 2013
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Son’s kidney donation to his mother the ultimate gift
Noah Harrison donated a kidney to his mother, Erica Johnson, earlier this week. (Photo by John Russell) For as long as Noah Harrison can remember, he has made all of his mother’s Christmas, birthday and other special occasion gifts by hand. But this year, Harrison’s gift for… Read MoreDec 20, 2012
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Kidney woes during heart failure
Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure. Read MoreNov 8, 2012
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Obesity linked to kidney problems after heart surgery
Obesity increases the risk of acute kidney injury following cardiac surgery, according to a Vanderbilt study published in the Journal of the American Society of Nephrology. Read MoreJul 3, 2012
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Low oxygen could protect sick kidneys
Low oxygen – and the activation of factors that respond to this situation – may be protective in chronic kidney disease. Read MoreJun 28, 2012
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Young stem cells counter kidney aging
Young bone marrow cells alleviate aging-related kidney changes in mice. Read MoreDec 15, 2011