Journal Publication
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Inherited lung disease no worse in offspring
An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations. Read MoreNov 15, 2012
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Kidney woes during heart failure
Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure. Read MoreNov 8, 2012
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Bacterial signals in sarcoidosis
Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death. Read MoreNov 6, 2012
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Toxin provides endometriosis clues
Environmental toxins may contribute to endometriosis-related infertility by disrupting endometrial response to progesterone. Read MoreNov 2, 2012
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Protein’s length, flexibility key to infection
The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells. Read MoreOct 31, 2012
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Bid protein guards blood cells against stress
A protein normally known to promote cell death found to encourage survival of blood forming cells. Read MoreOct 25, 2012
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Stomach bug alters tumor suppressor
The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer. Read MoreOct 23, 2012
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Setting traps to probe gene function
A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function. Read MoreOct 18, 2012
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Amish aid search for Alzheimer’s genes
An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease. Read MoreOct 11, 2012
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Complementary and alternative medicine use differs by race, economics
Use of complementary and alternative medicine differs by race and socioeconomic factors, study reports. Read MoreOct 9, 2012
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Host proteins can control HIV infection
The protein APOBEC3G contributes to spontaneous control of HIV-1 in vivo and may provide therapeutic benefits. Read MoreOct 5, 2012
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Proteins help flip tumor’s invasive switch
Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together. Read MoreOct 4, 2012
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An orphan enzyme’s purpose
“Orphan” enzyme may play role in cancer growth, new research suggests. Read MoreOct 4, 2012
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Target acquired for aggressive tumor
New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified. Read MoreSep 27, 2012
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Cell entry ports for cold virus
The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells. Read MoreSep 25, 2012
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HER2 may impact lung cancer therapy
A protein associated with aggressive breast cancers may also influence resistance of lung cancer to targeted therapies. Read MoreSep 21, 2012
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How ‘Jedi’ disposes of dead neurons
The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system. Read MoreSep 19, 2012
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Cells with LIP eat their neighbors
A transcription factor called LIP is capable of causing one cell to consume another. Read MoreSep 13, 2012
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Enzyme counters stomach acid attack
Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease. Read MoreSep 11, 2012
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Parkinson’s therapy may impact language
Deep brain stimulation used to treat Parkinson’s disease may impair some aspects of language processing, a recent study suggests. Read MoreSep 7, 2012