Journal Of Virology
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Study finds RSV may evade vaccines via rapid mutation
A Vanderbilt study concluded that RSV’s ability to mutate rapidly to escape detection by the body’s immune system makes it more challenging to design and develop vaccines that can stop it from spreading. Read MoreMar 9, 2023
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Early steps in reovirus replication
Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read MoreOct 6, 2020
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Evolution of a deadly virus
Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans. Read MoreMay 23, 2018
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Keep your coat on, virus!
A compound acting on serotonin receptors delays a critical step during reovirus cell entry, reducing viral infectivity. Read MoreSep 22, 2015
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Contributors to coronavirus ‘fitness’
Understanding the role that host membrane modification plays in coronavirus replication is essential for developing novel approaches to block the viruses that cause SARS and MERS. Read MoreFeb 24, 2015
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Targeting HIV’s “cap”
New findings underscore the attractiveness of the HIV capsid – the structure that encloses the viral genome – as a therapeutic target. Read MoreFeb 10, 2015
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Natural killer cells don’t clear HMPV
Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments. Read MoreJul 23, 2014
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Respiratory virus vaccine candidate
Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus. Read MoreMay 27, 2014
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Target cell entry to halt Chikungunya virus
Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications. Read MoreApr 28, 2014
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Protein’s length, flexibility key to infection
The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells. Read MoreOct 31, 2012
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Cell entry ports for cold virus
The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells. Read MoreSep 25, 2012