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Journal of Clinical Investigation Archives

Breast cancer study explores therapy to slow recurrence

Mar. 21, 2013—Many patients with triple-negative breast cancer (TNBC) have recurrence of their disease after an initial response to chemotherapy because the cancer cells have become resistant to treatment. TNBC has a lower survival rate because of this pattern of resistance and there are no targeted agents to treat this form of breast cancer.

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Health and Medicine Reporter Research


Linking oxygen, iron and red blood cells

Feb. 6, 2013—The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

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Health and Medicine Reporter Research


Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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Health and Medicine Reporter Research


New therapeutic target for cold, flu viruses identified

Aug. 9, 2012—Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs. Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells.

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Heart protein may be target for colon cancer therapies

Oct. 7, 2011—A protein critical in heart development may also play a part in colon cancer progression.

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Health and Medicine Reporter Research


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