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Journal of Clinical Investigation Archives

VU study explores inflammation, hypertension link

Feb. 12, 2015—The evidence is increasing: the immune system and inflammation are key contributors to high blood pressure.

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Gene mutation linked to breast cancer therapy resistance

Nov. 20, 2014—A group of Vanderbilt-led investigators has identified a new gene mutation that may explain why some breast cancer patients do not respond to anti-hormone therapy.

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Team spots trigger for rare diarrheal disease in infants

Jul. 24, 2014—Researchers at Vanderbilt University, the University of Arizona and Phoenix Children’s Hospital have discovered what triggers a rare but devastating diarrheal disease in newborns that is fatal without intravenous feeding or intestinal transplant.

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Study examines therapeutic bacteria’s ability to prevent obesity

Jul. 17, 2014—Engineered bacteria that produce a therapeutic compound in the gut prevent obesity in mice, Vanderbilt University investigators have discovered.

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Health and Medicine myVU myVU News Reporter Research


Molecular ‘chat’ holds kidney fibrosis clues

Jul. 10, 2014—A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.

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Study tracks new lung cancer drug target

Apr. 10, 2014—Researchers at Vanderbilt University have identified a potential new drug target in subtypes of lung cancer that are difficult to treat.

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Protein’s role in spread of colon cancer studied

Apr. 3, 2014—One of the most formidable weapons in a cancer’s arsenal is the ability to spread to other organs.

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Small molecule protects kidney filter

Mar. 19, 2014—A compound identified at Vanderbilt has therapeutic potential in protecting the kidney filter barrier.

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Studies shed new light on breast cancer development

Feb. 20, 2014—Rebecca Cook, Ph.D., assistant professor of Cancer Biology, has spent her life trying to understand what makes things grow, from seedlings in soil to tumor cells in the body.

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Health and Medicine Reporter Research The Vanderbilt Story


Researchers identify novel biomarker for diabetes risk

Sep. 17, 2013—Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease.

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Study tracks skin salt’s role in blood pressure control

Jun. 6, 2013—Clinical pharmacologist Jens Titze, M.D., and his colleagues have identified a new cast of cells and molecules that function in the skin to control sodium balance and blood pressure.

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Study lays groundwork for rational T cell vaccine design

May. 30, 2013—Vanderbilt University investigators have developed a new strategy for identifying the “bits” of a pathogen that spark a protective immune response.

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