Joshua Denny
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Studies combine genetic testing, electronic health records to find undiagnosed diseases
Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations. Read MoreApr 28, 2022
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Building a cohort, the easy way
An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions. Read MoreJan 7, 2021
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Gregor Mendel would be proud
A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do. Read MoreDec 12, 2019
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Getting the goods on obesity
Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read MoreNov 19, 2019
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Launch event helps introduce ‘All of Us’ initiative to Nashville
On Sunday, May 6, Nashville played an important role in the nationwide launch of “All of Us,” the National Institutes of Health’s (NIH) research program that aims to collect the health information of 1 million or more research participants. Read MoreMay 10, 2018
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VUMC plays major role in nationwide ‘All of Us’ program
In 1969 the United States was the first nation to land a man on the moon. Forty-nine years later this country is poised to take another “giant leap” for humankind, this time by unleashing a revolution in medical research and human health. Read MoreMay 10, 2018
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Gene study spots clues to heart risk for statin patients
A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol. Read MoreMay 3, 2018
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Event set to launch ‘All of Us’ personalized medicine initiative
The All of Us Research Program, which aims to accelerate the prevention and treatment of illness through precision medicine with the help of a million or more research participants across the United States, officially opens for national enrollment Sunday, May 6. Read MoreMay 3, 2018
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Six Vanderbilt physicians honored by medical societies
Four faculty members of Vanderbilt University School of Medicine were among 78 physician-scientists inducted into The American Society for Clinical Investigation (ASCI), an elite honor society of physician-scientists from the upper ranks of academic medicine and industry. They are: Read MoreMay 3, 2018
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Denny, Wilkins to discuss precision medicine at next Discovery Lecture
Joshua Denny, M.D., M.S., and Consuelo Wilkins, M.D., MSCI, will discuss the potential of “precision medicine” during the next Vanderbilt Cutting-Edge Discovery Lecture on Thursday, Oct. 12. Read MoreOct 5, 2017
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Scientists create unique disease ‘catalog’ linked to immune system gene variations
A study led by researchers at Vanderbilt University Medical Center (VUMC) and the University of Arizona College of Pharmacy has generated the first comprehensive catalog of diseases in a single population associated with variations in HLA genes that regulate the body's immune system. Read MoreMay 10, 2017
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Denny named to list of top experts in health information technology
Joshua Denny, M.D., M.S., professor of Biomedical Informatics and associate professor of Medicine at Vanderbilt, has been named to an annual list of the 50 leading experts in health care information technology by Health Data Management, a trade news publication. Read MoreJan 12, 2017
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Neanderthal DNA has subtle but significant impact on human traits
The first study that directly compares Neanderthal DNA in the genomes of a significant population of adults of European ancestry with their clinical records confirms that this archaic genetic legacy has a subtle but significant impact on modern human biology. Read MoreFeb 11, 2016
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Vanderbilt’s Denny set for next Flexner Discovery Lecture
Joshua Denny, M.D., M.S., who helped propel Vanderbilt University Medical Center into a leadership role in the national Precision Medicine Initiative, will deliver the next Flexner Discovery Lecture on Thursday, Feb. 4. Read MoreJan 28, 2016
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E-records shed light on drug response
Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response. Read MoreMar 31, 2014
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New computer speeds clinical data collection
Tucked in a data center in the basement of Vanderbilt University Hospital, a new computer the size of a large armoire, called a data warehouse appliance, is delivering a new order of speed to Vanderbilt clinical scientists as they search, filter, analyze and annotate the de-identified medical records of approximately 2 million patients. Read MoreApr 25, 2013
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VUMC’s Denny lands award from informatics group
Joshua Denny, M.D., M.S., assistant professor of Biomedical Informatics and Medicine and a key contributor to Vanderbilt University’s personalized medicine initiative, is the 2012 recipient of the New Investigator Award from the American Medical Informatics Association (AMIA). Read MoreNov 8, 2012
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Tool helps plumb electronic records
A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies. Read MoreAug 24, 2012