Jonathan Mosley
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Study evaluates polygenic risk score for prostate cancer risk prediction
A Vanderbilt study found that prostate cancer polygenic risk score has limited utility for enhancing prostate cancer screening. Read MoreMar 16, 2023
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For more precise drug treatments, ‘squeeze’ the genome: study finds
Large-scale studies will be required to identify the complexity of genetic variations that affect how patients respond to a given drug and whether they will have side effects, according to researchers at Vanderbilt University Medical Center. Read MoreJul 22, 2021
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Study finds certain genetic test not useful in predicting heart disease risk
A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk. Read MoreFeb 27, 2020
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Research bolsters thyroid function, atrial fibrillation link
Jonathan Mosley and colleagues have found that genetic varations in thyroid function can increase the risk of an irregular heart rhythm. Read MoreJan 31, 2019
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Team’s study reveals hidden lives of medical biomarkers
The hidden lives of medical biomarkers are the focus of a recent study in Nature Communications by Jonathan Mosley. Read MoreOct 11, 2018
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Researchers chart new informatics path in tracking disease risk
In a study in Circulation: Cardiovascular Genetics, Vanderbilt University’s Jonathan Mosley, M.D., Ph.D., and colleagues use genetic correlation to hitch together two unrelated sets of data, one from a longstanding epidemiological cohort and the other from electronic health records. Read MoreFeb 23, 2017