Jeffrey Rathmell
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Obesity-cancer connection discovery suggests strategies for improving immunotherapy
The study reported in the journal Nature provides a mechanistic explanation for the “obesity paradox” — that obesity can contribute to cancer progression but also improve response to immunotherapy. Read MoreJun 13, 2024
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Twelve at Vanderbilt are among world’s highly cited researchers
Twelve current investigators at Vanderbilt University Medical Center and Vanderbilt University are on this year’s list of scientists whose papers have been cited the most frequently by other researchers. Read MoreNov 15, 2023
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Vanderbilt-led team receives 2023 Endeavor Award from The Mark Foundation for Cancer Research
A multidisciplinary team of investigators has received a 2023 Endeavor Award from The Mark Foundation for Cancer Research to support four closely linked projects exploring the fundamental mechanisms that drive the obesity-cancer connection, Read MoreOct 24, 2023
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Vanderbilt team tracks cellular and antibody responses to COVID-19 vaccine
A collaborative team of Vanderbilt researchers has characterized the antigen-specific immune response to the Pfizer SARS-CoV-2 RNA vaccine. The group used multiple single-cell technologies, unbiased machine learning and traditional immunological approaches to track cellular and antibody responses in samples collected over time from a cohort of healthy participants. Read MoreJul 20, 2022
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CRISPR screen identifies new anti-inflammatory drug target
A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics. Read MoreNov 11, 2021
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Study revises understanding of cancer metabolism
Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years. Read MoreApr 7, 2021
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Eight Vanderbilt faculty elected AAAS fellows for 2019
Eight Vanderbilt University faculty members have been named 2019 fellows of the American Association for the Advancement of Science, an honor bestowed upon AAAS members by their peers. Read MoreNov 26, 2019
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Rathmell, Hasty to address New York Academy of Sciences Oct. 22
Jeffrey Rathmell, Cornelius Vanderbilt Chair in Pathology, Microbiology and Immunology, will be a keynote speaker at the “Targeting Immunometabolism in Autoimmune Diseases and Inflammation” conference at The New York Academy of Sciences in New York City Oct. 22. Read MoreOct 18, 2019
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Center for Immunobiology grows, bolsters program
The Vanderbilt Center for Immunobiology has relaunched its mission with a greater focus on human immunology, an endeavor supported by additional researchers, more funding support and designation as a Center of Excellence. Read MoreJul 18, 2019
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Team’s findings show glutamine metabolism affects T cell signaling
Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases. Read MoreNov 1, 2018
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Grant bolsters kidney cancer immunotherapy research
W. Kimryn Rathmell, MD, PhD, Cornelius Abernathy Craig Professor of Medicine and director of the Division of Hematology and Oncology at Vanderbilt-Ingram Cancer Center (VICC), has received a grant to research the role of immunosuppression in the tumor microenvironment for kidney cancer. Read MoreMay 10, 2018
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Links between immune cells and metabolism explored
At the intersection of immunology and metabolism is a burgeoning new field: immunometabolism. It’s an area where Vanderbilt has exceptional strengths, said Jeffrey Rathmell, Ph.D., Cornelius Vanderbilt Professor of Immunobiology. Read MoreNov 10, 2016
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Celebration honors nine endowed chair recipients
Nine faculty members who hold endowed chairs were honored and donors were thanked during a festive celebration Sept. 26 at the Student Life Center. Read MoreSep 28, 2016
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Restore T cells to fight leukemia
Modulation of T cell metabolism thus may represent a new therapeutic avenue for leukemia patients. Read MoreSep 14, 2016
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VICC investigators in spotlight at AACR conference
A top Vanderbilt-Ingram Cancer Center (VICC) investigator recently met with Vice President Joe Biden regarding the National Cancer Moonshot Initiative, a major national program to identify, fund and accelerate the most promising research leading to cancer cures. Read MoreMay 19, 2016
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Rathmell to lead new Center for Immunobiology
Jeffrey Rathmell, Ph.D., has been recruited to Vanderbilt University Medical Center (VUMC) to lead a new Center for Immunobiology, a structure supported by the Department of Pathology, Microbiology and Immunology, the Department of Medicine and Vanderbilt-Ingram Cancer Center (VICC). Read MoreAug 20, 2015