James Crowe Jr.

Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus. Read More

With the help of a computer program called “Rosetta,” researchers at Vanderbilt University have “redesigned” an antibody that has increased potency and can neutralize more strains of the AIDS-causing human immunodeficiency virus (HIV) than can any known natural antibody. Read More

Vanderbilt University researchers have received a five-year, $9 million grant from the National Institutes of Health (NIH) to design more effective flu vaccines and novel antibody therapies. Read More

Vanderbilt University researchers have joined a multi-center effort led by Pennsylvania-based Inovio Pharmaceuticals Inc. to accelerate development of potential antibody therapies against the often-lethal Ebola virus. Read More

Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola. Read More

During the past five years, Vanderbilt University Medical Center has become a leader in “personalized medicine,” the use of genomic information to individualize patient care. Read More

In the latest VUCast: Learn why overweight women lose in the workplace -- especially when it comes to pay; see breakthrough weapons in the fight against infectious diseases; and hear music legend Sheryl Crow speak about her craft. Watch now! Read More

  Nancy Brown, M.D. Vanderbilt University’s Nancy J. Brown, M.D., chair and physician-in-chief of the Department of Medicine, and James E. Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, are among 70 new members elected to the Institute of Medicine (IOM), the organization… Read More

Don’t panic over Ebola. But don’t ignore it, either. That was the take-home message for U.S. citizens from a “mini-hearing” held by U.S. Sen. Lamar Alexander, R-Tenn., at Vanderbilt University Medical Center on Wednesday with researchers and health officials from Vanderbilt and the State of Tennessee. Read More

Vanderbilt University researchers have partnered with Mapp Biopharmaceutical Inc. to develop new human antibody therapies for people exposed to the deadly Ebola and Marburg viruses. Read More

(Vanderbilt University) Potentially “game-changing” research at Vanderbilt University on infectious diseases, population health and health policy will be showcased during two interactive presentations May 15 and May 22. A segment of the Flexner Discovery Lecture Series, the new “Vanderbilt Cutting-edge Discovery” discussions are highlights of recent presentations… Read More

World Health Day 2014 Shines Spotlight on Mosquito-borne Viral Diseases Female Ades aegypti mosquito. Photo courtesy of the CDC Image Library. Chikungunya virus, a vector-borne disease that is quickly spread by mosquitoes and causes victims to suffer severe fever and pain, has reached the… Read More

Vanderbilt University researchers are collaborating in a multi-center, federally-funded project to develop ways to treat and prevent the highly lethal Ebola and Marburg virus infections. Read More

Vanderbilt University scientists have contributed to a major finding, reported this week in the journal Nature, which could lead to the first effective vaccine against respiratory syncytial virus (RSV), a significant cause of infant mortality. Read More

A worrisome new avian influenza virus, called H7N9, emerged this spring in Eastern China. Read More

Vanderbilt vaccine researchers are using gold nanotechnology to develop a new approach to making vaccines. Read More

A careful look at how the body’s natural defenses disarm virulent strains of influenza hints at the possibility of a way to fight the flu. Read More

Targeting diabetes that develops after a stem cell transplant may help moderate graft-vs.-host disease, an adverse effect of the procedure, and improve outcomes. Read More

New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly. Read More

Antibodies to the 2009 H1N1 influenza strain reveal new insights into how antibody diversity forms and functions, with possible implications for designing flu vaccines. Read More