James Crowe Jr.
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Six from Vanderbilt to speak at TEDxNashville March 17–18
Astrophysicists, artists, celebrity chefs and clinical psychologists will be among the speakers at the eighth annual TEDxNashville. Read MoreJan 25, 2017
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Early study finds antibody that ‘neutralizes’ Zika virus
Researchers at Vanderbilt University Medical Center and Washington University School of Medicine in St. Louis have isolated a human monoclonal antibody that in a mouse model “markedly reduced” infection by the Zika virus. Read MoreNov 7, 2016
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Investigators create ‘Trojan Horse’ to fight Ebola
A multi-center research team including scientists from the Vanderbilt Vaccine Center has come up with a clever “Trojan Horse” strategy for thwarting the highly lethal Ebola virus. Read MoreSep 8, 2016
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Research team takes aim at Ebola virus ‘decoy protein’
Using an antibody generated at Vanderbilt University Medical Center that neutralizes the Ebola virus, researchers at the Scripps Research Institute in La Jolla, California, have determined the structure of a “decoy” protein that may enable the virus to evade detection by the immune system. Read MoreAug 11, 2016
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Vanderbilt and Human Vaccines Project launch initial studies to decode the human immune system
Researchers at Vanderbilt University Medical Center this month began recruiting volunteers to participate in a clinical trial aimed at decoding the human “immunome,” the genetic underpinnings of the immune system. Read MoreJun 21, 2016
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Potent HIV antibodies suggest new vaccine development approach
It’s been known for some time that the immune system can produce antibodies capable of “neutralizing” HIV, and stopping the AIDS-causing virus dead in its tracks. Read MoreApr 7, 2016
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Vanderbilt researchers identify potential antibody treatment for H7 avian flu
Researchers at Vanderbilt University Medical Center have isolated human antibodies against a type of bird flu that has killed more than 200 people in China since 2012 and which may pose a worldwide pandemic threat. Read MoreMar 7, 2016
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Antibodies may be ‘silver bullet’ for Ebola viruses
There may be a “silver bullet” for Ebola, a family of hemorrhagic viruses, one of which has killed more than 11,000 people in West Africa in the past two years. Read MoreJan 21, 2016
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Caucus explores crucial role of NIH research funding
James Crowe Jr., M.D., director of the Vanderbilt Vaccine Center, and Anthony Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID), recently participated in a U.S. Senate National Institutes of Health (NIH) caucus briefing held in Washington, D.C., by Senate NIH caucus co-chairs Sens. Lindsey Graham (R-SC) and Dick Durbin (D-IL). Read MoreDec 3, 2015
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Two Ebola Survivors’ Blood Could Help Vanderbilt Researchers Find A Treatment
Vanderbilt researchers could be one step closer to finding a way to fight the deadly Ebola virus – thanks to two Ebola victims from Nigeria, who faced death and survived. Vanderbilt researchers developed a unique method of isolating potent Ebola-fighting antibodies from survivors’ blood and they believe these newest… Read MoreOct 19, 2015
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Survivors of Ebola outbreak take part in VUMC vaccine study
Two survivors of a 2014 Ebola outbreak in Nigeria visited Vanderbilt University Medical Center last week to share their experiences and participate in a study aimed at finding ways to treat the often-fatal infection. Read MoreSep 24, 2015
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Ebola symposium to feature Nigerian physicians
Three Nigerian physicians who survived Ebola virus disease in July 2014 after coming in direct contact with an Ebola-infected patient will speak at Vanderbilt University Medical Center next Wednesday, Sept. 16. Read MoreSep 10, 2015
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How to trick a wily virus
Vanderbilt investigators have discovered how human antibodies induced during testing of an experimental “bird flu” vaccine kill the virus. Read MoreJul 24, 2015
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Study could lead to vaccine for mosquito-borne dengue virus
Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus. Read MoreJul 9, 2015
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Vanderbilt researchers develop potential treatment to fight mosquito-borne chikungunya virus
In late 2013 the Caribbean had its first case of the mosquito-borne chikungunya virus. Today there have been almost 1.2 million cases in 44 countries or territories, including 177 cases in 31 U.S. States. Read MoreJul 8, 2015
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‘Redesigned’ antibodies may control HIV: study
With the help of a computer program called “Rosetta,” researchers at Vanderbilt University have “redesigned” an antibody that has increased potency and can neutralize more strains of the AIDS-causing human immunodeficiency virus (HIV) than can any known natural antibody. Read MoreMay 21, 2015
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VU lands $9 million NIH grant to design better flu vaccines
Vanderbilt University researchers have received a five-year, $9 million grant from the National Institutes of Health (NIH) to design more effective flu vaccines and novel antibody therapies. Read MoreMay 15, 2015
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VU joins national effort to speed Ebola therapy testing
Vanderbilt University researchers have joined a multi-center effort led by Pennsylvania-based Inovio Pharmaceuticals Inc. to accelerate development of potential antibody therapies against the often-lethal Ebola virus. Read MoreApr 8, 2015
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Studies show human antibodies can fight lethal Marburg virus
Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola. Read MoreFeb 26, 2015
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Core facilities key driver of VUMC research gains
During the past five years, Vanderbilt University Medical Center has become a leader in “personalized medicine,” the use of genomic information to individualize patient care. Read MoreJan 29, 2015