Oct. 9, 2014—Vanderbilt investigators have discovered a new type of immune cell residing in the intestinal epithelium that may function as a first line of defense against ingested pathogens.
Apr. 17, 2014—Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.
Nov. 8, 2013—Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. difficile toxin, TcdB, induces rapid cell death of human colon cell lines and pig colonic...
May. 14, 2012—The epithelial cells that line the intestines have a newly discovered mechanism for protecting us against microbes: they fire anti-bacterial "bullets" into the gut.