Imported-post
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Using billing codes to count cancers
The billing codes in electronic health records are useful for counting skin cancers over time — an important metric for cancer risk assessment and prevention. Read MoreSep 2, 2021
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Rheumatoid arthritis drug combined with standard of care may help reduce mortality for hospitalized COVID-19 patients
Hospitalized patients with COVID-19 who received the rheumatoid arthritis drug baricitinib, in combination with the standard of care including corticosteroids, died less often than those receiving only the standard of care, according to a study released this week. Read MoreSep 2, 2021
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Discovery offers insight for development of cancer therapies targeting mutant p53
The tumor suppressor protein p53 is mutated in more than half of all human cancers. Several drugs that potentially can restore mutant p53 to its normal cancer-killing function are in clinical investigation. Read MoreSep 2, 2021
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Study shows gene-drug interactions are common
When a drug or combination of drugs causes different responses in different people, genetic variation is often at play. Pharmacogenomics, through discovery of genetic risk and use of clinical genotyping, aims to reduce trial-and-error approaches to drug prescribing. Read MoreSep 2, 2021
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Engineering doctoral students experience paradigm-shifting clinical training in surgery and intervention
Trainees gain big picture knowledge plus work closely with surgeons The results are in: Five cohorts of Vanderbilt engineering doctoral students have experienced ‘paradigm-shifting training’ in surgery and intervention. Preliminary reports from a five-year program of intensive training, supported by a nearly $1 million National Institute of Biomedical Imaging and Bioengineering grant, show strong evidence... Read MoreAug 27, 2021
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Research Snapshot: How will the global community react if vulnerable nations pioneer solar radiation geoengineering
By Marissa Shapiro THE IDEA Jonathan Gilligan (John Russell) Jonathan Gilligan, associate professor of Earth and environmental sciences and civil and environmental engineering, and a group of international researchers have illustrated potential international conflicts over climate change. One of a larger group of studies, this work engaged in a role-playing scenario set in 2040 in... Read MoreAug 24, 2021
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Research Snapshot: How will the global community react if vulnerable nations pioneer solar radiation geoengineering
By Marissa Shapiro THE IDEA Jonathan Gilligan (John Russell) Jonathan Gilligan, associate professor of Earth and environmental sciences and civil and environmental engineering, and a group of international researchers have illustrated potential international conflicts over climate change. One of a larger group of studies, this work engaged in a role-playing scenario set in 2040 in... Read MoreAug 24, 2021
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Royal Society award gives international exposure to work in polar sciences, computational mechanics
The School of Engineering’s work in polar and climate science, plus computational mechanics, will get international exposure with a two-year travel grant from the Royal Society, the independent academic society of the U.K., for a collaboration between a Vanderbilt professor and a professor in England. The project will establish new approaches for simulating fracture propagation... Read MoreAug 20, 2021
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Team isolates antibodies that target alphaviruses
A multi-institutional team led by researchers at Vanderbilt University Medical Center has isolated monoclonal antibodies that prevent infection by alphaviruses, including the often-lethal Eastern equine encephalitis virus. Read MoreAug 19, 2021
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Potential protection from atherosclerosis
Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins. Read MoreAug 19, 2021
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New departments answer growing demand in computer science, computational science, electrical engineering
Music Row becomes Technology Row The School of Engineering has created two new departments from the Department of Electrical Engineering and Computer Science to encourage innovation, accommodate enrollment growth, and focus on areas of strategic excellence. The existing degree programs in computer science will be housed in the new Department of Computer Science chaired by... Read MoreAug 18, 2021
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Study reveals missing link between high-fat diet, microbiota and heart disease
A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science. Read MoreAug 12, 2021
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Vitamin D impact on disease biomarkers
In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease. Read MoreAug 10, 2021
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Sudden death from deep in the brain?
Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy. Read MoreAug 9, 2021
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Motor protein linked to intestinal cell differentiation
The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. Read MoreAug 5, 2021
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Gene expression in diabetic nephropathy
Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read MoreAug 5, 2021
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Study finds genetic factor undermines H. pylori treatment
Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Read MoreAug 4, 2021
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Discovery points to new avenues to kill aggressive cancer cells
Chemoresistant SW480 colon cancer cells stained for lipid rafts (green), death receptor 4 (red) and cell nuclei (blue). Image taken by Joshua Greenlee using a Zeiss LSM 880 from the Vanderbilt Cell Imaging Shared Resource Center. By Marissa Shapiro THE IDEA Vanderbilt faculty and researchers are looking for the “Achilles’ heel” of the cancer cells... Read MoreAug 3, 2021
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Discovery points to new avenues to kill aggressive cancer cells
Chemoresistant SW480 colon cancer cells stained for lipid rafts (green), death receptor 4 (red) and cell nuclei (blue). Image taken by Joshua Greenlee using a Zeiss LSM 880 from the Vanderbilt Cell Imaging Shared Resource Center. By Marissa Shapiro THE IDEA Vanderbilt faculty and researchers are looking for the “Achilles’ heel” of the cancer cells... Read MoreAug 3, 2021
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Prediction models for breast cancer
Vanderbilt researchers developed new prognostic models for breast cancer outcomes and found that adding postdiagnostic weight change as a factor improves the prediction. Read MoreJul 27, 2021