Immunotherapy
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Colorectal cancer ‘cartography’ reveals an avenue to improved immunotherapy
Vanderbilt University Medical Center researchers have discovered why most colorectal tumors escape detection and destruction by the body’s immune system. Read MoreDec 8, 2023
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Tumor antigens key to improving cancer immunotherapy: study
Vanderbilt researchers are working to better design immune therapies that attack tumors without also attacking healthy normal tissue in patients. Read MoreNov 17, 2023
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Study finds hallmarks of T cell exhaustion within hours of tumor exposure
Vanderbilt researchers found that that T cells become “exhausted” within hours of encountering a tumor, challenging existing ideas about how T cells become dysfunctional. Read MoreAug 3, 2023
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A “torque” for tumor blood vessels
Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read MoreAug 20, 2020
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Wilson awarded Komen breast cancer research grant
An engineering professor has received financial support from Susan G. Komen for breast cancer research. His project is among 60 grants totaling $26 million awarded to researchers nationwide. Those initiatives are focused on improving outcomes for metastatic breast cancer, reducing disparities in survivorship and developing new, more effective treatments. John T. Wilson, assistant professor of... Read MoreSep 25, 2019
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New prostate cancer treatment concept
Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer. Read MoreAug 22, 2019
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Cancer immunotherapies expert Allison set for Discovery Lecture
James Allison, PhD, whose work led to the development of cancer immunotherapies known as “checkpoint inhibitors,” will deliver the next Flexner Discovery Lecture on Thursday, March 8. Read MoreMar 1, 2018
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STINGing combination for cancer
A novel immunotherapy combination induced remarkable regression of tumors in a mouse model of head and neck cancer. Read MoreJun 19, 2017
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Richmond to speak at national VA research conference on cancer immunotherapy
Vanderbilt University cancer researcher Ann Richmond, Ph.D., 2016 recipient of one of the highest honors for scientific achievement bestowed by the U.S. Department of Veterans Affairs, will be a keynote speaker during a national VA research conference next week at Vanderbilt University School of Medicine. Read MoreMay 11, 2017
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Vanderbilt investigator lands Stand Up To Cancer grant for “smart” nanoparticles cancer research
John Wilson, Ph.D., assistant professor of Chemical and Biomolecular Engineering and of Biomedical Engineering at Vanderbilt University, has received an Innovative Research Grant from Stand Up To Cancer (SU2C). Wilson is among 10 early-career scientists to receive the grant awards focused on immuno-oncology. Read MoreApr 3, 2017
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Protecting the blood-brain barrier
Vanderbilt investigators have discovered how a promising cancer immunotherapy causes brain swelling, findings that could lead to ways to protect brain function while fighting cancers. Read MoreDec 9, 2016
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Improving natural killer cancer therapy
A newly discovered mechanism that helps cancer cells avoid destruction by immune system cells may improve immunotherapies. Read MoreApr 29, 2016
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Melanoma response to immune therapy
Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read MoreMar 3, 2016
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VICC Annual Retreat focuses on immunotherapy
Efforts to enable the immune system to “see” the cancer and attack the aberrant cells were the prime focus during Vanderbilt-Ingram Cancer Center’s Annual Retreat, held April 30 at the Vanderbilt University Student Life Center. Read MoreMay 21, 2015