Heart Rhythm
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Arrhythmia culprit: supertrafficking ion channel
Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities. Read MoreApr 15, 2021
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Robotic technology speeds arrhythmia gene classification
Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions. Read MoreJun 12, 2020
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New view of the heartbeat
Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias. Read MoreApr 6, 2018
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Long QT syndrome – revealed
Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders. Read MoreMar 12, 2018
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Mutation raises heart block risk
A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care. Read MoreMar 3, 2017
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Normalizing calcium flux to treat atrial fibrillation
A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation. Read MoreMay 12, 2014
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Keeping the beat after heart surgery
Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery. Read MoreFeb 10, 2014
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Rhythm response tied to gene variant
A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder. Read MoreJun 21, 2013
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Study tracks genes involved in heart rhythm disorders
A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm. Read MoreFeb 7, 2013