Health And Medicine

A study by Vanderbilt researchers has identified genomic alterations in early stage adenocarcinomas of the lung that may indicate whether the lesions develop into aggressive tumors. Read More

Variation in the levels of hormones called natriuretic peptides may contribute to racial differences in susceptibility to diabetes, suggesting that this hormone system may be a target for reducing risk of the disease. Read More

Vanderbilt University Medical Center is teaming up with academic, governmental and corporate partners in an unprecedented, fast-tracked global effort to develop antibody-based treatments to protect people exposed to the 2019 novel coronavirus disease, COVID-19. Read More

Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders. Read More

Spasticity — a consequence of stroke and other disorders of the central nervous system — may be underdiagnosed and undertreated in nursing home residents. Read More

Vanderbilt researchers have identified haplotypes, ancestral fragments of DNA, that are associated with hereditary prostate cancer in a first-of-its-kind genomic study made possible by the study of prostate cancer patients with family histories of the disease. Read More

New insights on influenza genome packaging could guide strategies for interfering with the virus's life cycle and ability to cause infection. Read More

Researchers at Vanderbilt University Medical Center are playing a key role in the development of a potential new antiviral drug to treat COVID-19. Read More

Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation. Read More

This is not the Jedi you're thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain. Read More

Red and processed meat intakes are strongly associated with increased risk of sessile serrated polyps, which are not as well studied as conventional adenomas. Read More

Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth. Read More

A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients. Read More

A Polygenic Risk Score — a genetic assessment that doctors have hoped could predict coronary heart disease (CHD) in patients — has been found not to be a useful predictive biomarker for disease risk. Read More

Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat. Read More

Katherine Gifford, PsyD, MS, assistant professor of Neurology, has been awarded a five-year, $4.3 million research grant from the National Institute on Aging to study what subjective cognitive decline can reveal about underlying pathology. Read More

The Genetics Society of America has recognized Seth Bordenstein, an evolutionary geneticist and microbiologist at Vanderbilt, for an initiative that brings real-world scientific research into middle school, high school and college biology classes. Read More

An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests. Read More

The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target. Read More

An opioid-restrictive prescribing protocol reduced the number of postoperative opioid prescriptions and the oral morphine equivalent per prescription. Read More