Health And Medicine
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Rare tumor disguised as benign
A rare tumor that causes facial weakness was found masquerading as a more common benign facial tumor. Read MoreJan 26, 2021
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An interacting factor in leukemia
A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found. Read MoreJan 25, 2021
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Inflammation in genetic epilepsy
Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments. Read MoreJan 21, 2021
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WIN for blocking cancer growth
William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth. Read MoreJan 21, 2021
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Mitochondrial stress and hypertension
Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential. Read MoreJan 12, 2021
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Microbial RNA and rheumatoid arthritis
Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases. Read MoreJan 11, 2021
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Vitamin D activation and cancer risk
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read MoreJan 7, 2021
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Building a cohort, the easy way
An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions. Read MoreJan 7, 2021
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A deeper look at out-of-home care
Geographically targeted efforts to prevent children being placed in out-of-home care might be possible, Vanderbilt researchers report. Read MoreDec 15, 2020
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Polymer protection for heart muscle
Vanderbilt researchers demonstrate that the polymer P188 has promise as a therapy to prevent reperfusion injury — the cellular damage that occurs when blood flow returns after an ischemic event like a heart attack. Read MoreDec 14, 2020
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Model students: improving clinical decision-making
Vanderbilt investigators have devised a system to alert health IT teams to deteriorating performance in clinical prediction models. Read MoreDec 10, 2020
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Exploiting viral vulnerabilities
The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections. Read MoreDec 10, 2020
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Study sheds light on diabetes and COVID interaction
COVID-19 has been linked to cases of new-onset diabetes, diabetes-related emergencies and a higher death rate among diabetes patients. Read MoreDec 10, 2020
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Study details early events of inflammatory response
Vanderbilt University Medical Center investigators have identified a key molecular player in the early events of the inflammatory response to infection. The findings suggest new therapeutic possibilities for enhancing the inflammatory response to protect against pathogens and for blocking inflammation gone awry in diseases like arthritis and atherosclerosis. Read MoreDec 10, 2020
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Vanderbilt University Medical Center’s Crowe receives 2020 “Golden Goose” Award for COVID-19 research
James Crowe Jr., MD, a physician-scientist at Vanderbilt University Medical Center who has pioneered development of human monoclonal antibodies as potential treatments for viral diseases, has won a 2020 “Golden Goose” Award. Read MoreDec 1, 2020
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Hot spots identified for colorectal cancer mortality rates among young women
Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology. Read MoreNov 23, 2020
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A cohort for type 2 diabetes studies
A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs. Read MoreNov 17, 2020
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Imaging “biomarker” for Alzheimer’s disease progression
Changes in connectivity in the brain’s white matter may be a novel neuroimaging biomarker for assessing Alzheimer’s disease progression. Read MoreNov 16, 2020
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Consuelo Wilkins’ transformative public health engagement methods recognized with National Academy of Medicine election
Consuelo Hopkins Wilkins, professor of medicine in the School of Medicine and vice president for health equity at Vanderbilt University Medical Center, has received one of the highest honors in health and medicine. Read MoreNov 13, 2020
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New therapeutic target for lung cancer
Vanderbilt researchers have identified a new molecular partner — and potential therapeutic target — in a signaling axis that drives lung cancer. Read MoreNov 12, 2020