Guoqiang Gu

  • Vanderbilt University

    Keeping beta cells “fit”

    Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression. Read More

    Jul 9, 2020

  • Closeup shot of an African American man testing his blood sugar level

    New role for microtubules in diabetes

    Microtubules, part of the cell's cytoskeleton, regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes. Read More

    Jul 29, 2019

  • x-ray of a pancreas highlighted in red

    Building a pancreas

    Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop. Read More

    Jan 17, 2019

  • green traffic light

    Microtubules act as cellular ‘rheostat’ to control insulin secretion

    Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell. Read More

    Dec 3, 2015