Gastroenterology

A study by Vanderbilt researchers has revealed how metabolic changes spurred by fatty acids contribute to the transformation of cells into abnormal versions of themselves that are the precursors to stomach cancer. Read More

Researchers at Vanderbilt University Medical Center have uncovered evidence of fibroblast cells' direct involvement in the development of gastric cancer. Read More

Researchers at Vanderbilt University Medical Center have discovered a potential new target in the fight against colorectal cancer, the nation’s third most common malignancy and, next to lung cancer, the second leading cancer killer. Read More

Vanderbilt researchers found that chronic use of opioid painkillers like hydrocodone and oxycodone significantly increases the risk of dysphagia, or difficulty swallowing. Read More

Eunyoung Choi, PhD, assistant professor of Surgery, and colleagues identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cells are a key source of clonal evolution of dysplasia to multiple types of gastric cancer. Read More

A selenium transport protein produced in the colon may be a novel biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease. Read More

Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo. Read More

It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection. Read More

Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori. Read More

Researchers at Vanderbilt University Medical Center have generated the first comprehensive molecular “atlas” of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract. Read More

Single-cell and multisystem analysis leads cell biologists at Vanderbilt to new understanding of rare cells, with potential inflammation-reducing therapeutics for Crohn’s disease and IBD patients. Read More

Appendiceal cancer — cancer of the appendix — is a rare malignancy that is usually found during surgery for acute appendicitis. Although the rate of appendectomies has been stable over the last two decades, the incidence of malignant appendiceal cancer increased 232% in the United States. Read More

Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. A new study breaks down this risk according to specific ethnicities and locations within the stomach. Read More

For Charleston, S.C., gastroenterologist Dr. Will Bulsiewicz, the human gut, literally, is the key to health. Read More

Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented. Read More

The gut has its own built-in pacemakers, populations of specialized cells that control smooth muscle contraction in the stomach, small intestine and colon. Read More

As a gastroenterologist, Christopher Lind, M.D., says he is often the “butt” of jokes, but few people truly appreciate the role the gut plays in their happiness. Read More

Richard Peek, M.D., director of the Vanderbilt Digestive Disease Research Center, has been appointed to a five-year term as editor-in-chief of the medical journal Gastroenterology beginning July 2016. Read More

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read More

Children with stomach troubles grow up to be anxious adolescents and young adults, according to a recent study. Read More