Galina Lepesheva

The lab of Professor of Biochemistry Fred Guengerich has proposed a paradigm shift in the understanding of a critical chemical reaction involved in sterol biosynthesis. Read More

A detailed structural and functional analysis of the yeast protein that is the main target of antifungal drugs will help direct efforts to develop better treatments. Read More

Structural and molecular details of an anti-fungal target's interaction with inhibitors suggest ways to design better treatments for fungal infections. Read More

It’s possible to cure Chagas disease – a deadly tropical infection transmitted by “kissing bugs” – in a mouse model. Read More

Kissing Bug (Photo courtesy of the Centers for Disease Control and Prevention) Chagas disease, a deadly tropical infection caused by the protozoan parasite Trypanosoma cruzi and transmitted by biting insects called “kissing bugs,” has begun to spread around the world, including the U.S. Yet current treatment is… Read More