Featured-Reporter
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VUMC researchers upend dogma about vasopressin production
Vanderbilt investigators have discovered that vasopressin, which has long been thought to be produced only in the brain, is also produced in the kidney. Read MoreJan 5, 2023
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Novel therapeutic target identified for chronic kidney disease
Vanderbilt investigators have discovered a molecular mechanism that promotes chronic kidney disease following kidney injury. Read MoreDec 15, 2022
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Study links excess oxygen during anesthesia to risk of organ injury
A Vanderbilt study found that higher levels of excess oxygen given to patients under general anesthesia add risk of injury to the kidneys, lungs and heart. Read MoreNov 30, 2022
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Study sheds light on the development of inflammation, high blood pressure and resulting kidney damage.
Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the development of inflammation, high blood pressure and resulting kidney damage. Read MoreOct 20, 2022
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Study finds that reducing intake of simple sugars improves GERD
A Vanderbilt study found that reducing dietary carbohydrates improved both symptoms and objective measurements of gastroesophageal reflux disease (GERD) in a randomized controlled trial. Read MoreOct 6, 2022
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Study suggests new mechanism for lipid transporter
A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought. Read MoreSep 15, 2022
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Researchers discover how salt increases blood pressure
A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension. Read MoreAug 17, 2022
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C. difficile may contribute to colorectal cancer: study
A Vanderbilt study found that the bacterium Clostridioides difficile (C. difficile) may be a previously unrecognized contributor to colorectal cancer. Read MoreJul 28, 2022
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Researchers find potential new target against colorectal cancer
Researchers at Vanderbilt University Medical Center have discovered a potential new target in the fight against colorectal cancer, the nation’s third most common malignancy and, next to lung cancer, the second leading cancer killer. Read MoreJul 21, 2022
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Vanderbilt team tracks cellular and antibody responses to COVID-19 vaccine
A collaborative team of Vanderbilt researchers has characterized the antigen-specific immune response to the Pfizer SARS-CoV-2 RNA vaccine. The group used multiple single-cell technologies, unbiased machine learning and traditional immunological approaches to track cellular and antibody responses in samples collected over time from a cohort of healthy participants. Read MoreJul 20, 2022
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Studies combine genetic testing, electronic health records to find undiagnosed diseases
Combining genetic testing with information from electronic health records revealed undiagnosed heart rhythm disorders and new conditions associated with inherited cancer gene mutations. Read MoreApr 28, 2022
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Vanderbilt University, Medical Center reach $1B milestone together in research funding
Faculty at Vanderbilt University and Vanderbilt University Medical Center achieved a significant milestone in 2021: more than $1 billion in research funding awarded from external organizations. Read MoreApr 5, 2022
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High blood pressure genes improve heart surgery survival in children
Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery. Read MoreMar 24, 2022
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VUMC researchers find clue to drug-induced arrhythmias
Vanderbilt University Medical Center researchers have made a fundamental discovery about how the heart compensates for genetic variations that otherwise could trigger abnormal and potentially fatal heart rhythms. Read MoreFeb 24, 2022
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Gene variants increase risk of kidney failure in Black veterans with COVID-19: study
Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19. Read MoreFeb 10, 2022
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Study identifies molecular trigger of severe injury-induced inflammatory response
Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure. Read MoreJan 19, 2022
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Thyroid cancer paper lands national recognition
Researchers in the Endocrine Neoplasia Research Laboratory at Vanderbilt University Medical Center have received national recognition for their work to discover better treatments for thyroid cancer. A paper describing their lab work was awarded first place in the Basic Science category at the 2021 Cancer Research Competition. Read MoreDec 2, 2021
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Study links depression scores, white blood cell count
Researchers across four health care systems, including Vanderbilt University Medical Center, have found that increased depression polygenic scores are associated with increased white blood cell count, highlighting the importance of the immune system in the etiology of depression. Read MoreDec 2, 2021
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Study provides new insight into how antidepressant drugs work
A study by Vanderbilt researchers sheds light on how current antidepressant drugs work and suggests a new drug target in depression. Read MoreDec 1, 2021
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CRISPR screen identifies new anti-inflammatory drug target
A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics. Read MoreNov 11, 2021