Eric Delpire
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Study explores possible drug target for neurological problems
A team at Case Western Reserve University and Vanderbilt University Medical Center has determined with atomic-level precision how two established drugs bind to and alter the conformation of a cell membrane transporter protein called NKCC1, shutting down its activity. Read MoreNov 3, 2022
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Vanderbilt-Ancora partnership advances research for rare form of epilepsy
Research in the Weaver lab leads to discoveries that help secure partnership with Ancora Innovation LLC. “Vanderbilt is at the forefront of genetic research. By understanding the genetic causes of disease opens exciting new opportunities to develop drugs to treat them more effectively,” said Matt Nelson, vice president, genetics and genomics, 3DC at Deerfield Management. Read MoreOct 27, 2022
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Transporter’s role in gut barrier
A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections. Read MoreApr 21, 2020
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Transporter mutation alters cell energy
A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered. Read MoreFeb 20, 2020
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Blueprint for treating epilepsy
Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders. Read MoreNov 14, 2019
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Study tracks sodium-potassium pathway
A six-member group of biomedical scientists from Europe and the United States, including Eric Delpire, PhD, MS, professor of Anesthesiology, has been awarded a $6 million grant to study the role of dietary potassium in hypertension. Read MoreJan 25, 2018
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Directorships honor VUMC’s critical missions
Vanderbilt University Medical Center (VUMC) on Monday held its first Directorship Celebration to honor and support eight of its leaders in clinical care, research, education and administration. Read MoreJan 25, 2018
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New culprit in nerve degeneration
Vanderbilt researchers have discovered that regulation of cell volume plays a role in nerve degeneration and peripheral neuropathies. Read MoreAug 12, 2016
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Team tracks how kidney responds to blood pressure meds
Changes in the kidney can limit the blood pressure-lowering effects of thiazide diuretics, a new study reports. Read MoreApr 30, 2015
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Neuronal culprit in genetic disease
A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered. Read MoreOct 14, 2014
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Research becomes personal for Delpire
Eric Delpire, Ph.D., professor of Anesthesiology, Molecular Physiology and Biophysics and director of the Anesthesiology Basic Science Research Division, has spent the past 15 years developing genetically altered mice for use in scientific research, and he now knows the value of his research in a very personal way. Read MoreDec 6, 2012
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Record number elected AAAS fellows
Seventeen members of Vanderbilt University’s faculty have been elected fellows of the American Association for the Advancement of Science (AAAS) this year. Read MoreNov 29, 2012