Epigenetics
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New tool probes gene regulation
Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. Read MoreFeb 6, 2020
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“Idling” cancer cells may return
Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment. Read MoreApr 11, 2018
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Sweatt, Tansey discuss influence of epigenetics on research
Basic research underway at Vanderbilt University Medical Center is raising hopes that one day it will be possible to reverse memory loss in people with Alzheimer’s disease and stop a major driver of cancer in its tracks. Read MoreNov 2, 2017
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Epigenetics expert Allis set for Sept. 7 Discovery Lecture
Internationally known epigeneticist C. David Allis, Ph.D., will deliver the first Flexner Discovery Lecture of the academic year at 4 p.m. Thursday, Sept. 7, in room 208 Light Hall. Read MoreAug 31, 2017
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How Epo action is ‘enhanced’
The hormone erythropoietin (Epo) controls red blood cell production and synthetic forms of Epo treat multiple disorders. New Vanderbilt research details how Epo works. Read MoreJul 24, 2017
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Top cancer researchers reveal latest findings at VICC science retreat
Ordinary cells can be transformed into cancer cells through epigenetics — changes to DNA that turn genes on or off. Those gene changes can protect cells or make them vulnerable to disease processes including cancer. Read MoreMay 11, 2017
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Esophageal cancer complexities
New findings that reveal complex interactions in esophageal adenocarcinoma could lead to diagnostic, prognostic or therapeutic biomarkers. Read MoreMar 16, 2017
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Saliva test for obesity risk
“Epigenetic signatures” in DNA may present an opportunity for prevention of or early intervention in childhood obesity. Read MoreJan 24, 2017
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Vanderbilt historian offers unsettling look at bioengineered near future
Historian Michael Bess said that he found a whole new world of imminent advances in biotechnology that promise to transform society while he was researching 'Our Grandchildren Redesigned.' Read MoreDec 1, 2015
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Pioneers of Discovery: Investigator seeks to debug cancer’s ‘bad software’
Beyond genetics — that’s the call Oliver McDonald, M.D., Ph.D., heard during the year between college and medical school he spent in a lab at St. Jude Children’s Research Hospital in Memphis. Read MoreJan 9, 2014
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Dual-action enzyme protects esophagus
An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus. Read MoreMay 9, 2013
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New drugs a good BET for brain cancer
A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors. Read MoreMar 20, 2013
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Drugs reverse lung cancer cell changes
Drugs that target “epigenetic” changes may help treat or slow the progression of lung cancer. Read MoreFeb 1, 2012