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eLIFE Archives

Advanced imaging tools reveal architecture of cell division machinery

Nov. 9, 2017—Using super-resolution microscopy tools in the Nikon Center of Excellence, Vanderbilt investigators have determined the molecular architecture of the contractile ring machinery that functions during cell division — a process that is essential for life.

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Ancient sea creature unlocks a mystery of how tissue developed

Apr. 20, 2017—The dawn of the Animal Kingdom began with a collagen scaffold that enabled the organization of cells into tissues.

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Surprising finding by VU team sheds light on fibrotic disease

Jan. 19, 2017—Integrins are membrane proteins made up of combinations of different “alpha” and “beta” subunits that enable cells throughout the body to interact with their surroundings.

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Refining neural circuitry

Aug. 2, 2016—During development, neural circuits are remodeled – some synapses are eliminated and others are strengthened – to produce a mature, functional nervous system.

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COX-2 blocker could help PTSD

May. 12, 2016—COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.

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Study explores less invasive way to monitor colorectal cancer

Feb. 18, 2016—Investigators at Vanderbilt University Medical Center have published research regarding an important feature of colorectal cancer (CRC) that could eventually lead to the development of non-invasive means of monitoring cancer progression. After lung cancer, CRC is the second-most lethal cancer in the United States.

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How ABC transporters move molecules

Jun. 13, 2014—New views of how transporters move molecules across cell membranes are key to understanding how these proteins impact tumor cell drug resistance and inherited diseases such as cystic fibrosis.

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