DNA

A study led by Vanderbilt-Ingram Cancer Center investigators has identified a gene expression pattern that may explain why chemotherapy prior to surgery isn’t effective against some tumors and suggests new therapy options for patients with specific subtypes of breast cancer. Read More

Understanding how an environmental hazard damages DNA may shed light on processes of tumor formation. Read More

Vanderbilt University is already doing genetic analyses of patients to help in developing a shortlist of effective drugs, says Dr. William Schaffner, chairman of the department of preventive medicine at its medical school. Read More

A new tool will allow researchers to identify proteins involved in DNA replication and damage repair, processes that go awry in cancer. Read More

New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents. Read More

Children of childhood cancer survivors who were treated with radiation or some forms of do not have an increased risk for birth defects compared to children of cancer survivors who did not receive such treatments. Read More

Electrical engineer and physicist Yaqiong Xu has received a prestigious career development award to study a new class of molecules called nanobiohybrids. Read More

Structural studies are providing insight to how aflatoxin – a toxin produced by fungi – contributes to cancer development. Read More

An international team of scientists has identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of an important and very debilitating neurological disease. Read More

What if your doctor could tell by reading your genetic code which drugs were most likely to work for you, and which you should avoid, even before you try them? What if a “genetic biopsy” taken from your cancer could pinpoint the treatment most likely to kill the tumor, and… Read More