Diabetes
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Weight cycling increases diabetes risk
Alyssa Hasty, Cornelius Vanderbilt Professor of Molecular Physiology and Biophysics, specializes in immunometabolism, specifically on the role that the immune system plays in obesity and metabolic disease. Recent work from her lab explored the changes in immune cell populations in fat during obesity, weight loss, and weight cycling. Read MoreJul 19, 2022
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Study sheds light on the dark side of obesity
Vanderbilt research that promotes the anti-inflammatory pathway in macrophages could also reduce some of the bad side effects of obesity. Read MoreMay 12, 2022
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Gene expression in diabetic nephropathy
Vanderbilt researchers are looking to mRNA populations in podocytes — kidney cells that help filter blood — to help identify potential targets for treating diabetic kidney disease. Read MoreAug 5, 2021
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Beta cell regeneration
Vanderbilt researchers dissected the complex microenvironment of the pancreatic islet to discover the signals that drive beta cell regeneration — as a possible treatment for diabetes. Read MoreMay 20, 2021
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HIV, diabetes and immune cells in fat
In HIV-positive individuals with diabetes, immune cells in fat are more proinflammatory and cytotoxic and may represent a therapeutic target for diabetes. Read MoreMar 18, 2021
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Targeting glucagon action in diabetes
Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy. Read MoreMar 4, 2021
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Gene variant and glucose metabolism
Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study. Read MoreFeb 18, 2021
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Early research shows promise for therapeutics that delay Type 2 Diabetes
Discovering the mechanism behind cell behavior that is a hallmark of type 2 diabetes, Vanderbilt researchers move closer to treatments for the disease, which affects 34 million Americans. Read MoreJan 12, 2021
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Vanderbilt Diabetes Center seeks pilot and feasibility proposals to study interaction of SARS-CoV-2, diabetes
The Vanderbilt Diabetes Center, the NIH-funded Diabetes Research and Training Center, and the NIH-funded Center for Diabetes Translational Research seek pilot and feasibility proposals to study the interaction of SARS-CoV-2/COVID-19 and diabetes. Read MoreDec 16, 2020
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Study sheds light on diabetes and COVID interaction
COVID-19 has been linked to cases of new-onset diabetes, diabetes-related emergencies and a higher death rate among diabetes patients. Read MoreDec 10, 2020
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A cohort for type 2 diabetes studies
A study group of more than 600,000 patients with type 2 diabetes, identified from electronic medical records in the PCORnet national research network, could be valuable for assessing the safety of type 2 diabetes drugs. Read MoreNov 17, 2020
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New treatment for a rare obesity
Diabetes drugs known as GLP-1 receptor agonists, such as exenatide (Byetta), are a promising and safe treatment for a rare form of obesity. Read MoreNov 3, 2020
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Clue to diabetic kidney disease
Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read MoreOct 5, 2020
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Go for the Gold: How to determine your risk for diabetes
One in nine American adults has diabetes, and one in three has pre-diabetes. Prevention and early intervention can decrease the risk of complications down the road. Read MoreSep 11, 2020
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Vanderbilt historian explores impact of racism, classism on understanding diabetes
Research by Vanderbilt history professor Arleen Tuchman on the cultural history of diabetes offers important lessons for other public health challenges, including COVID-19. Read MoreAug 19, 2020
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Keeping beta cells “fit”
Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression. Read MoreJul 9, 2020
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Race, hormones and diabetes risk
Variation in the levels of hormones called natriuretic peptides may contribute to racial differences in susceptibility to diabetes, suggesting that this hormone system may be a target for reducing risk of the disease. Read MoreApr 8, 2020
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Post-transplant diabetes may be reversible: study
Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at VUMC report. Read MoreFeb 20, 2020
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Wellcast: Learn about new diabetes treatment technology
Shichun Bao, associate professor of medicine and the Diabetes Technology Program leader in the Division of Endocrinology at the Eskind Diabetes Clinic, shares information on the amazing technological advances in diabetes treatment and blood sugar management. Read MoreDec 11, 2019
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Genetic screen in worms reveals critical step in insulin synthesis
The identification of a protein important for insulin synthesis may hold clues for understanding the pathogenesis of diabetes. Read MoreDec 4, 2019