Department Of Biomedical Informatics
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Protein “pockets” help ID cancer genes
Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response. Read MoreNov 11, 2014
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VU study reveals shared pathways in psychiatric disorders
Schizophrenia and bipolar disorder share common genetic underpinnings. Vanderbilt researchers combined high-resolution gene expression studies with gene association data to reveal signaling pathways linked to schizophrenia and bipolar disorder. Read MoreSep 18, 2014
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Drug discovery clues in network map
Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies. Read MoreAug 5, 2014
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Lehmann to advise on health informatics
Chris Lehmann, M.D., professor of Pediatrics and Biomedical Informatics at Vanderbilt, has been appointed by the U.S. Government Accountability Office as the first pediatrician to serve on the Health Information Technology (HIT) Policy Committee. Read MoreMay 15, 2014
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E-records shed light on drug response
Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response. Read MoreMar 31, 2014
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Web tool speeds pulmonary hypertension discovery
The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis. Read MoreMar 5, 2014
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Informatics tools link protein structure, drug action: speaker
Russ Altman, M.D., Ph.D., professor of Bioengineering, Genetics and Medicine at Stanford University, posed an intriguing question at last week’s Discovery Lecture: is it possible to predict drug side effects from the 3D-structure of proteins? Read MoreFeb 13, 2014
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American College of Medical Informatics honors Denny, Harris
Faculty members Josh Denny, M.D., M.S., associate professor of Biomedical Informatics and Medicine, and Paul Harris, Ph.D., associate professor of Biomedical Informatics and research associate professor of Biomedical Engineering, are among six fellows elected this year to the American College of Medical Informatics. Read MoreDec 12, 2013
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What makes us human?
Using computational tools to search for the genetic basis of what makes us human, Vanderbilt Assistant Professor of Biomedical Informatics Tony Capra and colleagues at the University of California-San Francisco have identified promising candidate regions. Read MoreNov 22, 2013
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Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
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Pioneers of Discovery: Computer science drives Capra’s biomedical research
Tony Capra, Ph.D., is a new assistant professor of Biomedical Informatics and investigator in the Center for Human Genetics Research at Vanderbilt. His goal is to use the tools of computer science to address problems in genetics, evolution and biomedicine. Read MoreOct 3, 2013
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Gene interactions and cavities
Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay. Read MoreSep 30, 2013
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VUSM’s new curriculum gains technological support
Vanderbilt University School of Medicine has created a new office to manage the technical support necessary to make the dramatic shift in educational techniques under Curriculum 2.0. Read MoreAug 1, 2013
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Visualizing data on network ‘maps’
The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification. Read MoreJul 25, 2013
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Ehrenfeld to edit health care computing, IT journal
Jesse Ehrenfeld, M.D., MPH, associate professor of Anesthesiology, Surgery and Biomedical Informatics, has been named editor-in-chief of the Journal of Medical Systems, succeeding Ralph Grams, M.D., professor of Pathology and Medical Informatics at the University of Florida College of Medicine. Read MoreJun 27, 2013
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Diagnostic codes identify smoking status
Diagnostic codes used for billing purposes effectively identify smokers in a general clinic population and can be used to adjust smoking status in genetic and epidemiologic studies. Read MoreMar 15, 2013
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Middleton named VU Health System informatics chief
Blackford Middleton, M.D., MPH, M.Sc., corporate director of clinical informatics research and development at Partners Healthcare in Boston, will join Vanderbilt later this month in the role of assistant vice chancellor for Health Affairs and chief informatics officer for Vanderbilt University Health System. He succeeds John Doulis, M.D. Read MoreFeb 21, 2013
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Two from VUMC help lead national informatics group
Vanderbilt’s Department of Biomedical Informatics remains exceptionally well represented on the nine-member executive committee of the American College of Medical Informatics (ACMI). Read MoreFeb 14, 2013
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Proteins help flip tumor’s invasive switch
Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together. Read MoreOct 4, 2012
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Network approach yields glioblastoma clues
MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor. Read MoreAug 9, 2012