Department Of Biological Sciences

This past academic year, seven graduate students and one undergraduate student participated in the 2025 Merck Compound Challenge. Created in 2018, the competition gives teams from around the world 48 hours to create a proposed route of chemical steps from a commercial chemical they believe will make the final compound. Read More

Pet parrots often outlive their owners, and Vanderbilt researchers want to know why—because uncovering the biological mechanisms behind exceptional longevity could one day help safely extend the lives of humans. With the support of a new $1.3 million grant from the W.M. Keck Foundation, Vanderbilt biologist Gianni Castiglione is taking a bold approach to aging research: reverse-engineering how birds live three to four times longer than similarly sized mammals to identify safe, effective genetic targets for human aging therapies. Read More

A recent study from the labs of Lars Plate and Jens Meiler, published in the Proceedings of the National Academy of Sciences of the United States of America, analyzed both selectively responsive and poorly responsive variants of cystic fibrosis and revealed the molecular determinants of drug response. Read More

Danial Asgari, a postdoctoral researcher in the Tate Lab, and Ann Tate, associate professor of Biological Sciences, recently published a study in Molecular Biology and Evolution titled “How the Structure of Signaling Regulation Evolves: Insights from an Evolutionary Model.” Their findings show that negative feedback loops (or NFLs) acting closer to a cell’s final decisions, such as turning genes on or off, are especially resistant to evolutionary change. Read More

Our past has something to say. 2025 Guggenheim Fellow Larisa DeSantis is ready to translate. Read More

New work from the Castiglione lab and that of collaborator, Elia Duh (Johns Hopkins), is shaping the way is shaping the way we understand the evolutionary limits of energy production. He discovered that the horse, an oft-studied, physiological powerhouse, evolved an enigmatic and ancient mutation that enables horses and their relatives to produce extreme amounts of energy while avoiding deleterious side effects. Read More

In a groundbreaking study led by Sarah Worthan, Ph.D., a postdoctoral researcher in the Behringer Lab at Vanderbilt University, scientists have successfully evolved microbial cultures that possess the ability to sense pH changes, enabling rapid responses to environmental fluctuations. Read More

New research led by recent Vanderbilt Ph.D. alumna Maria Luísa Jabbur from the Johnson Lab and BBSRC Discovery Fellow at the John Innes Centre, in the UK has uncovered that even cyanobacteria—tiny organisms with a generation time of just five to six hours—can sense and respond to changes in light availability, or photoperiod, to gear up for winter. Read More

Thirteen innovative projects across seven colleges and schools have been selected for the spring 2024 round of Seeding Success internal grants. The Office of the Vice Provost for Research and Innovation announced the recipient list on May 31. Read More

The Vanderbilt Graduate Student Council has announced the winners of the 2024 Graduate Leadership Anchor Awards, honoring the hard work and leadership of Vanderbilt graduate students schoolwide. This year’s awards recognize outstanding service, mentorship, departmental leadership, research and best overall. Read More

A mere decade ago, decoding the genome of every organism in a major branch of the tree of life and deciphering their diets was a pipe dream. In a groundbreaking study, a team of researchers from Vanderbilt University, the University of Wisconsin-Madison and other institutions worldwide have done just that for the first time ever. Led by Abigail LaBella, a postdoctoral researcher in the Rokas Lab, an international research team used the genomes and diets of nearly all known species from an ancient lineage of yeasts to understand the evolution of generalists and specialists.  Read More

Tucked behind the 6 Magnolia Building on Vanderbilt’s Peabody Campus is what might look to some like a lush garden of weeds. In reality, it’s a strategic Native Meadow full of pollinator-friendly plants. Since its inception, the meadow has flourished, and many faculty, staff and students have found ways to collaborate and interact with the space, thought of as a ‘living lab.’ Read More

The distinguished faculty members and deans representing eight colleges and schools were presented with medallions that symbolize the attainment of their positions and will become part of their official academic regalia. Chair holders contribute their expertise to real-world challenges, including climate change, political inequality and access to justice, artificial intelligence and ICU trauma.   Read More

The highly selective Beckman Scholars Program is celebrating 15 years of partnership with the College of Arts and Science. Over the years, the Arnold and Mabel Beckman Foundation has provided more than $543,000 in support of 23 undergraduate Beckman Scholars at Vanderbilt who engage in unique, hands-on, mentored research. Read More

The contributions of Quarterman and her graduate students to our understanding of the Middle Tennessee cedar glade ecosystem and the comeback of the critically endangered Tennessee coneflower are just part of her well-deserved legacy. Read More