Crohn’s Disease

Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss. Read More

Steven Townsend, associate professor of chemistry, and Fang Yan, research professor of pediatrics and cell and development biology, have discovered how a sugar in human breast milk mitigates damage to the small intestines caused by chemotherapy-induced mucositis. Read More

A selenium transport protein produced in the colon may be a novel biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease. Read More

Single-cell and multisystem analysis leads cell biologists at Vanderbilt to new understanding of rare cells, with potential inflammation-reducing therapeutics for Crohn’s disease and IBD patients. Read More

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease. Read More

An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients. Read More

A documentary to be screened at this year’s Nashville Film Festival will give audiences the opportunity to experience the life of a vivacious young woman making the biggest decision of her life: whether to risk rare and complicated surgery with the potential to radically change her life. Read More

ResearchMatch, the nationwide online medical research volunteer recruitment and engagement service hosted by Vanderbilt University Medical Center, has announced a partnership with the Crohn’s & Colitis Foundation of America (CCFA), a volunteer-driven organization dedicated to curing Crohn’s disease and ulcerative colitis. Read More

Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation. Read More

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases. Read More

A protein isolated from beneficial bacteria found in yogurt and dairy products could offer a new, oral therapeutic option for inflammatory bowel disorders. Read More