COX-2
-
Better adenoma detection
Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans. Read MoreMay 4, 2023
-
Reversing stress-related anxiety
Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders. Read MoreFeb 14, 2019
-
COX-2 ‘conjugate’ may slow growth of some tumors: study
More than a decade after the anti-inflammatory drugs Vioxx and Bextra were pulled from the market because of a heightened risk of heart attack and stroke in some patients, COX-2 inhibitors may be on the verge of a comeback, this time as anti-cancer agents. Read MoreJan 19, 2017
-
Imaging probe for retinal disease
An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness. Read MoreOct 12, 2016
-
COX-2 blocker could help PTSD
COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression. Read MoreMay 12, 2016
-
The yin and yang of COX-2
New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs. Read MoreOct 2, 2015
-
Lit up COX-2 cancer probe
A new imaging probe developed by Vanderbilt investigators enhances tumor visibility and has broad applications in diagnosing and monitoring patients with cancer. Read MoreJun 17, 2015
-
Low-dose aspirin’s protective effect in cancer explained
For years, scientists have known that regular aspirin use may reduce the risk of cancer. Read MoreOct 2, 2014
-
Vanderbilt scientists discover potential new way to treat anxiety
Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural “endocannabinoids” without gastrointestinal side effects, Vanderbilt University scientists will report next week. Read MoreAug 5, 2013
-
Urine biomarker for colon cancer?
A molecule detectable in urine may be helpful in diagnosing colon cancer. Read MoreMar 10, 2012