Colon Cancer
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Better adenoma detection
Fluorescent nanoparticles clearly identified colonic adenomas — precursors to colorectal cancer — in mice, and the formulation should translate to clinical use in humans. Read MoreMay 4, 2023
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Discovery points to new avenues to kill aggressive cancer cells
Chemoresistant SW480 colon cancer cells stained for lipid rafts (green), death receptor 4 (red) and cell nuclei (blue). Image taken by Joshua Greenlee using a Zeiss LSM 880 from the Vanderbilt Cell Imaging Shared Resource Center. By Marissa Shapiro THE IDEA Vanderbilt faculty and researchers are looking for the “Achilles’ heel” of the cancer cells... Read MoreAug 3, 2021
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Discovery points to new avenues to kill aggressive cancer cells
Chemoresistant SW480 colon cancer cells stained for lipid rafts (green), death receptor 4 (red) and cell nuclei (blue). Image taken by Joshua Greenlee using a Zeiss LSM 880 from the Vanderbilt Cell Imaging Shared Resource Center. By Marissa Shapiro THE IDEA Vanderbilt faculty and researchers are looking for the “Achilles’ heel” of the cancer cells... Read MoreAug 3, 2021
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Research Snapshot: Discovery points to new avenues to kill aggressive cancer cells
Vanderbilt researchers discover that protein-coated nanoparticles kill more than half of cancer cells in the blood of patients with advanced chemo-resistant colon cancer. Est. reading time: 2.5 mins. Read MoreAug 3, 2021
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Vitamin D activation and cancer risk
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read MoreJan 7, 2021
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New markers of colorectal cancer risk
Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo. Read MoreOct 29, 2020
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Blocking tumor ‘signals’ and ‘fuel’
Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read MoreAug 25, 2020
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Meat intake and colorectal polyps
Red and processed meat intakes are strongly associated with increased risk of sessile serrated polyps, which are not as well studied as conventional adenomas. Read MoreMar 9, 2020
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Protein’s role in inflammation-related cancer studied
Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer. Read MoreAug 15, 2019
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SMAD4 clue to colon cancer
Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States. Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4. Read MoreJul 5, 2018
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Calcium intake and colorectal cancer
Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered. Read MoreOct 18, 2017
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Researchers find novel mechanism of resistance to anti-cancer drugs
Vanderbilt investigators have discovered a novel non-genetic cause of resistance to the targeted anti-cancer therapy cetuximab. Their findings, reported this week in Nature Medicine, suggest a strategy for overcoming this resistance. Read MoreOct 17, 2017
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Bile acids, microbiota and colon cancer
Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis. Read MoreJul 5, 2017
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Decorate your work area blue for Colon Cancer Awareness Month
March is National Colon Cancer Awareness Month. As a department, group-decorate your work area in blue to raise awareness for colon cancer screening. We want to see how you would remind people that colon cancer screening should begin at age 50. Read MoreMar 1, 2017
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Wear blue March 3 for Colon Cancer Awareness Month
Wear blue March 3 to show your support and raise awareness of colon cancer. Use this day to spread the word about colon cancer screening. Read MoreFeb 28, 2017
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Study links lifestyle factors to formation of high-risk polyps
Lifestyle factors like cigarette smoking and red meat consumption are known to be associated with an increased risk of colon polyps that can lead to colorectal cancer. Read MoreDec 8, 2016
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Free colon cancer awareness event is Aug. 5
For some people, cancer—especially colon cancer—is a persistent and potentially deadly visitor affecting family members from one generation to the next. Vanderbilt-Ingram Cancer Center, in partnership with the Colon Cancer Alliance, is hosting a free seminar to educate the public about risk factors associated with the disease. Read MoreJul 25, 2016
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Colon cancer awareness event set for Aug. 5
For some people cancer, especially colon cancer, is a persistent and potentially deadly visitor affecting family members from one generation to the next. Individuals who have a parent, sibling or child diagnosed with colon cancer have double the risk of developing the disease. Read MoreJul 25, 2016
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Singer’s concert honors care received at Cancer Center
A cancer patient’s gratitude toward his Vanderbilt-Ingram Cancer Center (VICC) physician led to a star-studded concert to benefit the Cancer Center. Read MoreMar 24, 2016
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‘Scope Out Colon Health’ expo is March 22
Visit the Scope Out Colon Health Expo from 11 a.m. to 1 p.m. Tuesday, March 22, in the Light Hall North Lobby to learn more about prevention, screenings and more. Read MoreMar 9, 2016