Clinical Trial

In 2011, doctors at the Vanderbilt Heart and Vascular Institute performed the state’s first transcatheter valve-replacement (TAVR) procedure for high-risk patients suffering from aortic stenosis, the most common valvular heart disease in the United States. Read More

Vanderbilt-Ingram Cancer Center (VICC) is leading a Phase 3 global trial of a cancer therapy that was initially tested and validated in a VICC research laboratory. One of the first patients treated with the therapy came to VICC after a bump on the head led to an unexpected cancer diagnosis. Read More

This month an international HIV prevention trial was launched that is testing the infection-preventing prowess of a monoclonal antibody called VRCO1. Read More

Among doctors, it is widely believed that a class of drugs called statins, which are used to lower cholesterol, might help patients tolerate the stress of cardiac surgery. Not so, according to a five-year, placebo-controlled, double-blinded randomized clinical trial conducted at Vanderbilt University Medical Center, published today in the… Read More

Kiersten Eaddy had long looked forward to her high school graduation day and joining her classmates to celebrate the accomplishment. Read More

Patients seeking to participate in clinical trials have a new option in online tools for finding studies that might offer hope for their problem or condition. Read More

Vanderbilt University Medical Center is participating in a national trial to see if outcomes for critically injured patients with uncontrolled bleeding can be improved by administering plasma to these patients while in flight to the hospital. Randomized patients who are at risk of hemorrhaging could receive… Read More

Pertussis, commonly known as whooping cough, is experiencing a resurgence, and its tiniest victims are not armed to battle the contagious respiratory infection. Read More

As the number of opportunities to participate in research studies continues to grow, the Vanderbilt Human Research Protection Program (HRPP) would like study participants to be aware of the Research Subjects’ Bill of Rights. Read More

A long-term Vanderbilt University Medical Center study of deep brain stimulation (DBS) in early-stage Parkinson’s disease has received approval from the Food and Drug Administration (FDA) to continue in a pivotal, phase III, large-scale safety and efficacy trial. Read More

Vanderbilt Heart and Vascular Institute is participating in a clinical trial to evaluate a medical device for the treatment of coronary artery disease. Read More

Vanderbilt University Medical Center will participate in a national trial to see if outcomes for critically injured patients with uncontrolled bleeding can be improved by administering plasma to these patients while in flight to the hospital. Read More

The IDIOM study is designed to compare how a diet with moderate caloric restriction, alone or with long-acting insulin, affects areas of the brain’s dopamine system that are involved in food intake, reward and the sense of pleasure people get from eating. Read More

Vanderbilt’s Eskind Diabetes Clinic has been selected to examine the ability of the drug abatacept to prevent type 1 diabetes (T1D). As part of the TrialNet consortium, Vanderbilt will be one of 14 North American sites observing the effects of the drug in people at high risk to develop T1D. Read More

Vanderbilt researchers propose guidelines for defining patient retention in clinical studies – an important parameter that affects study conclusions and program evaluations. Read More

The Vanderbilt Breast Center is piloting new measures to ensure continuity of care and timely insurance preauthorization as patients come off grant-sponsored clinical trial protocols and begin or resume standard care. Read More

ResearchMatch, a national on-line volunteer recruitment service hosted by Vanderbilt University, has launched a sub-registry for autism spectrum disorders (ASD) to increase the participation of children and adults with autism in clinical research studies. Read More

A newer version of an old class of blood pressure lowering drugs may offer advantages for obese patients with metabolic syndrome. Read More

ResearchMatch.org is a web-based registry that is connecting participants and researchers for clinical studies. Read More

This week on VUCast, Vanderbilt’s weekly newscast  highlighting  research, experts, students, sports and everything Vanderbilt: Laughing gas for labor Searching for alien planets What Vanderbilt WON at the Liberty Bowl [vucastblurb]… Read More