Center For Structural Biology
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Q&A: Illuminating a critical step in initiating DNA replication in eukaryotes
Brandt Eichman and Walter Chazin, professors of biochemistry, have worked together to provide a better understanding of how exactly DNA replication is initiated in eukaryotes. Using Vanderbilt’s state-of-the-art instrumentation in the Center for Structural Biology’s Cryo-Electron Microscopy Facility, Eichman, Chazin and their colleagues provided detailed visualizations of a multi-functional protein in action, which sheds light on how DNA replication is initiated in humans. Read MoreMar 15, 2024
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Exploring the basics of neurological disorders: Calcium transport in receptors
Led by Terunaga Nakagawa, an international collaboration describes for the first time the fundamental mechanism underpinning cellular processes that lead to learning and memory. Read MoreFeb 26, 2024
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Three Vanderbilt scientists awarded NIH grants for high-risk, high-reward research
Vanderbilt scientists Katherine Aboud, PhD’19, Breann Brown and Will Wan, PhD’14, have received 2021 National Institutes of Health Director’s Awards for their unconventional, bold approaches to research that advances knowledge and enhances health. Read MoreOct 5, 2021
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SARS-CoV-2 protein blocks an essential step in host gene expression, new discovery finds
Vanderbilt biochemist Yi Ren is part of a team that has identified a new behavior of a SARS-CoV-2 protein and discovered that interfering with its function can block virus replication in host cells. This opens up the potential for new therapeutic targets for COVID-19. Read MoreFeb 17, 2021
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Borden Lacy named director of Vanderbilt’s Center for Structural Biology
Borden Lacy, Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology, has been named director of the Vanderbilt Center for Structural Biology, effective Jan. 1. Read MoreJan 11, 2021
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Vanderbilt biochemists reveal the cause of Charcot-Marie-Tooth disease—too much of a good thing
Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people. Read MoreOct 27, 2020
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Biology researchers capture shape-shifting delivery structures in body’s cellular “FedEx system”
A new cellular biology study reports the first visualization of a unique shape-shifting structure in the human body which plays an important role in the timely delivery of fats and proteins. Read MoreMar 9, 2020