Cell Signaling

  • Human kidney cross section on scientific background. 3d illustration

    New insights into kidney development

    Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function. Read More

    Apr. 15, 2021

  • fat cells

    Vanderbilt research: Better understanding of fundamental cell behavior can improve drug development

    Gregor Neuert has discovered that cells respond differently to acute and gradual stress. This finding will transform how cell signaling is understood and inform the drug discovery processes. Read More

    Apr. 13, 2021

  • white light switch mounted on green wall

    A dual-purpose metabolic switch

    John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules. Read More

    May. 5, 2020

  • Vanderbilt University

    Team identifies ‘switch’ involved in DNA replication  

    DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.” Read More

    Feb. 23, 2017

  • Vanderbilt University

    DISSECTing cell signaling networks

    Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution. Read More

    Dec. 14, 2015

  • Vanderbilt University

    Framework for studying cell responses

    Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease. Read More

    Aug. 26, 2015

  • obesity or overweight belly

    New signaling pathway provides clues to obesity

    A Vanderbilt University-led research team has discovered a molecular “rheostat” in the brain’s appetite control center that may provide new insights into obesity, which is at epidemic levels in this country. Read More

    Jan. 22, 2015

  • Vanderbilt University

    Photo: Discovery Lecture

    David Clapham, M.D., Ph.D., of Boston Children’s Hospital and Harvard Medical School, discusses his research on ion channels and cell signaling at his recent Flexner Discovery Lecture. Read More

    Apr. 10, 2014