Cell Signaling

Vanderbilt University engineering professor Jonathan Brunger has won a National Science Foundation CAREER Award to understand how cells and biomaterials can work together to improve tissue regeneration. Read More

Integrin-linked kinase, a central component of a complex that coordinates cell signaling involved in migration, proliferation and cell death, plays a role in kidney development and epithelial cell function. Read More

Gregor Neuert has discovered that cells respond differently to acute and gradual stress. This finding will transform how cell signaling is understood and inform the drug discovery processes. Read More

John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules. Read More

DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.” Read More

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution. Read More

Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease. Read More

A Vanderbilt University-led research team has discovered a molecular “rheostat” in the brain’s appetite control center that may provide new insights into obesity, which is at epidemic levels in this country. Read More

David Clapham, M.D., Ph.D., of Boston Children’s Hospital and Harvard Medical School, discusses his research on ion channels and cell signaling at his recent Flexner Discovery Lecture. Read More