Cell Reports

James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis. Read More

According to a new study, the tiny zebrafish may hold the secret to regenerating damaged retinas in humans. Read More

Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells. Read More

Vanderbilt investigators and colleagues around the country have made a major discovery that could lead to better ways to treat type 1 diabetes (T1D). Read More

In childhood, asthma is more common in boys than girls. But around the time of puberty, that picture reverses. By mid-life women are twice as likely as men to have asthma. Read More

Vanderbilt researchers have identified a pathway that links excess sodium, inflammation and hypertension. Read More

Under the microscope, they sparkle like emeralds, these molecules that may hold a key to understanding — and stopping — cancerous growth. Read More

A protein that plays a powerful role in learning and memory may be a key to improving treatment of a rare autism spectrum disorder called Pitt-Hopkins syndrome (PTHS), a new study suggests. Read More

Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression. Read More

A new method developed at Vanderbilt may help “inventory” all tumor-promoting genes. Read More

Defining the genes required for the function of insulin-producing beta cells is crucial for ongoing efforts to develop a cell-based therapy for diabetes. Read More

A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.” Read More

A family of proteins with critical roles in cell division, synaptic transmission and cell migration don’t all function the way scientists thought they did, according to two new studies led by Vanderbilt researchers. Read More

Researchers at Vanderbilt University have discovered a new way to inhibit Hedgehog (Hh) signaling, an important regulatory pathway for vertebrate development – and cancer. Read More

Replenishing the supply of a molecule that normally activates cannabinoid receptors in the brain could relieve mood and anxiety disorders and enable some people to quit using marijuana. Read More

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered. Read More

Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered. Read More

David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes. Read More

Vanderbilt investigators used an in vivo screen in zebrafish to identify a potential new anti-cancer drug. Read More