Cell
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Colorectal cancer ‘cartography’ reveals an avenue to improved immunotherapy
Vanderbilt University Medical Center researchers have discovered why most colorectal tumors escape detection and destruction by the body’s immune system. Read MoreDec 8, 2023
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Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency
A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins. Read MoreMay 17, 2022
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Analysis reveals macrophages associated with kidney cancer recurrence
A white blood cell, the TREM2/APOE/C1Q-positive macrophage, has been identified as a potential biomarker to predict recurrence of the most common type of kidney cancer and as a possible target for drug development. Read MoreMay 24, 2021
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Study shows new COVID target could improve vaccines
Despite an impressive vaccination effort that exceeds 2 million shots a day, rates of COVID-19 are again on the rise in several parts of the United States, as is the spread of highly transmissible variants of the virus. Read MoreApr 1, 2021
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Exploiting viral vulnerabilities
The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections. Read MoreDec 10, 2020
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Shared genetics may shape treatment options for certain brain disorders
Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting. Read MoreJun 14, 2018
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Preparing for a return of pox
To prepare for the potential of a smallpox return, Vanderbilt researchers are isolating and studying naturally occurring antibodies from the blood of previously infected or immunized people. Read MoreOct 20, 2016
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Antibodies may be ‘silver bullet’ for Ebola viruses
There may be a “silver bullet” for Ebola, a family of hemorrhagic viruses, one of which has killed more than 11,000 people in West Africa in the past two years. Read MoreJan 21, 2016
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Investigators find clues to melanoma treatment resistance
Nearly half of all patients with malignant melanoma, the most deadly form of skin cancer, have a mutation in the BRAF gene found in their tumors. Mutations in the BRAF gene turn on a cancer growth switch known as the MAP kinase pathway. Read MoreOct 29, 2015
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Framework for studying cell responses
Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease. Read MoreAug 26, 2015
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Studies show human antibodies can fight lethal Marburg virus
Researchers at Vanderbilt University, the University of Texas Medical Branch at Galveston and The Scripps Research Institute for the first time have shown how human antibodies can neutralize the Marburg virus, a close cousin to Ebola. Read MoreFeb 26, 2015
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Team takes 4-D look at brain receptor’s role
Reporting last week in the journal Cell, researchers from Oregon Health and Science University, Harvard Medical School and Vanderbilt University describe the first “four-dimensional” picture of a brain receptor that plays a key role in learning and memory. Read MoreAug 14, 2014
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VU investigators confirm bromine’s critical role in tissue development
Twenty-seven chemical elements are considered to be essential for human life. Now there is a 28th — bromine. Read MoreJun 5, 2014
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Nutrient-absorbing surface’s assembly revealed: study
Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens. Read MoreApr 17, 2014
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Grad students help achieve key discovery
A multidisciplinary study conducted by the combined efforts of Vanderbilt University graduate students has led to the first evidence that abnormal messenger RNA export from the nucleus to the cytoplasm can cause human disease. Read MoreOct 24, 2013
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Cell source of heart’s blood vessels
An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart. Read MoreFeb 1, 2013
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Stem cell population may hold colon cancer clues
Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer. Read MoreMar 29, 2012
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Nanotechnologists take lessons from nature
Accepting and understanding natural variability is the key for engineers seeking to make nanoscale devices that are as efficient as living microorganisms. Read MoreApr 28, 2011