Cancer Research

A biomedical engineering professor has received a $1.9 million NIH grant to investigate the effects of mechanical stimuli such as shear stress on the behavior of cancer cells in blood flow. J. Lawrence Wilson Professor Mike King and his research group will develop the devices for the study as well as new cell lines to... Read More

Drug-tolerant persister cells–those that survive cancer treatment–found to rely on similar survival mechanisms across cancers, in a groundbreaking study led by Vanderbilt researchers. Read More

A bold engineering approach by a Vanderbilt University researcher to sort breast cancer cells based on their behavior first has produced compelling data that show less migratory cells create more metastases, contradicting the prevailing hypothesis on how cancer spreads. Read More

Vanderbilt researchers have developed what appears to be a simple and promising treatment for breast cancer metastasis. Read More

Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis. Read More

People with cancer sickened by COVID-19 have a crude death rate of 13%, according to the largest series of data released thus far from a multinational perspective. The data on more than 900 patients also revealed cancer-specific factors associated with increased mortality. Read More

An analysis of more than 140,000 people of European ancestry has identified blood protein biomarkers associated with prostate cancer risk. Read More

A study published June 17 in Nature offers clues as to why blocking inhibitory receptors on tumor-infiltrating T cells may not always work Read More

A report by researchers at Vanderbilt University Medical Center has shattered conventional wisdom about how cells, including cancer cells, shed DNA into the bloodstream. Read More

A randomized trial by Vanderbilt-Ingram Cancer Center researchers indicates that magnesium optimizes vitamin D status, raising it in people with deficient levels and lowering it in people with high levels. Read More

Vanderbilt (VU + VUMC, collaboratively) anticipates the opportunity to choose one nominee for the V Foundation 2018 Translational Research Award. Read More

Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read More

Graduate student Kyle Garland is diving into his studies with eight weeks of intense immunology research. Read More

A study led by Vanderbilt-Ingram Cancer Center (VICC) investigators suggests a drug combination which includes a PDK1 protein blocker may be more effective for breast cancer that has become resistant to cyclin-dependent kinase (CDK4/6) targeted therapy. Read More

Two Vanderbilt-Ingram Cancer Center (VICC) investigators have earned grant awards from The V Foundation for Cancer Research, continuing the foundation’s support for innovative cancer research initiatives at VICC. Read More

Scientists in the Vanderbilt Epidemiology Center (VEC) and Vanderbilt-Ingram Cancer Center (VICC) have been awarded a grant to plan and develop a Regional Center of Research Excellence in non-communicable diseases in Vietnam. Read More

Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers. Read More

Vanderbilt investigators have demonstrated that a certain protein complex drives tumor progression in aggressive breast cancers. Read More

Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets. Read More

Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients. Read More