Cancer Immunotherapy
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Waddell Walker Hancock Cancer Discovery Fund names Wilson and Rathmell as first scholars
A research endeavor that seeks to develop a new cancer immunotherapy utilizing nanobody delivery and targeted heating of tumors has received funding from the Waddell Walker Hancock Cancer Discovery Fund. The project to create an immunotherapy that will benefit more patients is led by John Tanner Wilson, left, and Jeffrey Rathmell. (photo by Donn Jones) […] Read MoreFeb 22, 2024
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Study finds hallmarks of T cell exhaustion within hours of tumor exposure
Vanderbilt researchers found that that T cells become “exhausted” within hours of encountering a tumor, challenging existing ideas about how T cells become dysfunctional. Read MoreAug 3, 2023
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Engineering professor to use $3M grant to develop technology to help cancer patients better fight disease
Associate Professor of Chemical and Biomolecular Engineering John Wilson has received a $3 million grant from the National Cancer Institute to develop technology that seeks to boost a person’s immune system to better fight cancer. Read MoreSep 6, 2022
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A “torque” for tumor blood vessels
Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies. Read MoreAug 20, 2020
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Potential new cancer target
Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis. Read MoreJun 4, 2020
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New prostate cancer treatment concept
Combining immunotherapy and radiation therapy may be a powerful treatment approach for castration-resistant prostate cancer. Read MoreAug 22, 2019
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Encephalitis identified as rare toxicity of immunotherapy treatment
Researchers are chronicling rare but serious toxicities that may occur with immune checkpoint inhibitors, the most widely prescribed class of immunotherapies. Read MoreJul 22, 2019
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Nanoparticle targets tumor-infiltrating immune cells, flips switch telling them to fight
A team of Vanderbilt University bioengineers announced a major breakthrough: designing a nanoscale particle that flips on cells' defenses to fight cancer. Read MoreJan 21, 2019
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Cancer immunotherapy drugs linked with more serious heart effects
Vanderbilt University Medical Center investigators have identified a growing number of serious and sometimes fatal cases of heart problems among cancer patients treated with some forms of immunotherapy. Read MoreMar 12, 2018